☆ Theoretical Approaches (20) ― Genetic contributions & Gene-Environmental Interaction Flashcards
Theoretical Approaches in Explaining the Etiology of Psychological Disorders (20)
long molecules of DNA at various locations on chromosomes, within cell nucleus
Genes
the chain-like structures within a cell nucleus that contain the genes
Chromosomes
carries of the information we inherit from our parents
Genes
… Chromosomes, … Pairs, … Pairs of Autosomes,
1 pair Sex Chromosomes
46 Chromosomes, 23 Pairs, 22 Pairs of Autosomes,
1 pair Sex Chromosomes
XX – , XY –
XX – female, XY – male
observable characteristics
Phenotypes
unique genetic makeup
Genotypes
naturally occurring variations of genes
Polymorphisms
influenced by multiple genes or by multiple polymorphisms of genes with any one gene having only very small effects
Polygenic
genetic mechanisms that ultimately contribute to the underlying problems causing the symptoms and difficulties experienced by people with psychological disorders
Endophenotypes
statistical analysis of family, twin, and adoption studies; if the disorder can be inherited and how much is attributable to genetics
Basic Genetic Epidemiology
studies the factors that influence the disorder
Advanced Genetic Epidemiology
what gene influences the behavior
Gene Finding
biological analysis of individual DNA samples; biological processes genes affect to produce symptoms of the disorder
Molecular Genetics
examine behavioral pattern or emotional trait in the context of the family
Family Studies
family member with the trait singled out for study
(The first person in the family to be identified as possibly having genetic disorder and who may receive genetic counseling or testing)
Proband
identify adoptees who have a particular behavioral pattern or psychological disorder and attempt to locate first-degree relatives who were raised in different family settings
Adoption Studies
usually conducted to identical twins because they share genetic makeup’
Twin Studies
Those people who reported more severe stressful life events and had at least one short allele of the 5-HTT gene were at greater risk of developing depression (Caspi et al., 2003)
serotonin-transporter gene
factors other than inherited DNA sequence, such as new learning or stress, that alter the phenotypic expression of genes
Epigenetics
individuals inherit tendencies to express certain traits or behaviors, which may then be activated under conditions of stress (Eric Kandel)
Diathesis-Stress Model
Diathesis-Stress Model
a condition that makes someone susceptible to developing disorder (vulnerability)
The higher vulnerability, the lesser life stress
needed to trigger traits
Diathesis
Diathesis-Stress Model
the response or experience of an individual to demands that he or she perceives as taxing or exceeding his or her personal resources
Disturbances stem from a genetic predisposition triggered by stress
Stress
Diathesis-Stress Model
cause of a disorder (i.e., situations that trigger the development of the disorder)
Predisposing Factor