The Pancreas Flashcards
___: the cells of the pancreas that carry out the exocrine function and therefore produce amylase, lipase, sodium bicarbonate, and other digestive enzymes
acinar cells
___: congenital anomaly of the pancreas that results in the maldevelopment of the pancreas in which the most ventral part of the pancreas encases the duodenum and may consequently lead to duodenal obstruction
annular pancreas
___: the recurring destruction of the pancreatic tissue that results in atrophy, fibrosis with scarring, and the development of calcification within the gland
chronic pancreatitis
___: inherited disorder that can affect the lungs, liver, pancreas, and other organs; this disorder changes how the body creates mucus and sweat
cystic fibrosis
___: coexisting enlargement of the common bile duct and pancreatic duct
double-duct sign
___: the accessory duct of the pancreas
duct of Santorini
___: the main pancreatic duct
duct of Wirsung
___: the first segment of the small intestine
duodenum
___: endoscopic procedure that utilizes fluoroscopy to evaluate the biliary tree and pancreas
endoscopic retrograde cholangiopancreatography
___: an islet cell tumor found within the pancreas
gastrinoma
___: elevated amylase
hyperamylasemia
___: the presence of elevated parathyroid hormone
hyperparathyroidism
___: bowel obstruction caused by the lack of normal peristalsis
ileus
___: an islet cell tumor found within the pancreas
insulinoma
___: small islands of tissue found within the pancreas that produce insulin and glucagon
islets of Langerhans
___: tumor found within the islets of Langerhans of the pancreas
islet cell tumors
___: a peritoneal cavity located between the stomach and pancreas where fluid can accumulate
lesser sac
___: the most common form of pancreatic malignancy, typically found within the head of the pancreas
pancreatic adenocarcinoma
___: congenital anomaly of the pancreas that results in a shortened main pancreatic duct that only works to drain the pancreatic head and not the entire pancreas
pancreatic divisum
___: the surgical procedure in which the head of the pancreas, the gallbladder, some of the bile ducts, and the proximal duodenum are removed because of a malignant pancreatic neoplasm; also referred to as the Whipple procedure
pancreaticoduodenectomy
___: a cyst surrounded by fibrous tissue that consists of pancreatic enzymes that have leaked from the pancreas
pancreatic pseudocyst
___: the peripancreatic fluid collection that results from the inflammation of the pancreas
phlegmon
___: a posteromedial extension of the pancreatic head
uncinate process
___: a hereditary disease that includes the
development of cysts within the pancreas and other organs
von Hippel–Lindau disease
___: the syndrome that includes an excessive secretion of acid by the stomach caused by the presence of a functional gastrinoma within the pancreas
Zollinger–Ellison syndrome
the pancreas is considered a ____ organ
retroperitoneal
the pancreas is both ___ and ___ gland
exocrine and endocrine gland
what are the exocrine functions of the pancreas
- digests carbs and converts starch to sugar
- digests fats and converts fats to fatty acids and glycerol
- neutralizes stomach acids
the ___ cells of the pancreas carry out the exocrine function of the gland
acinar
at the ___ the pancreatic digestive enzymes are mixed with bile from the liver
ampulla of vater
the opening of the sphincter of odd is triggered by what
cholecystokinin
the endocrine functions of the pancreas is performed by ____
islets of langerhans
the islets of langerhancs are composed of what cells
- alpha
- beta
- delta cells
the islets of langerhans produce what vital hormones
insulin and glucagon
what does glucagon do?
promotes the release of glucose by the liver which in turn increases blood sugar
the arterial blood supply to the head of the pan is via the ___
GDA
how do the body and tail of the pancreas review their blood
splenic and superior mesenteric arteries
venous drainage of the pancreas is achieved by ___
splenic vein, SMV, IMV, and portal vein
what cells promote the release of glucose by the liver
Alpha cells
alpha cells secrete ___
glucagon
beta cells secrete ___
insulin
delta cells secrete ____
somatostatin
normal echogenecity of the pancreas compared to the liver
slightly more echogenic than the liver
the AP diameter if the main pancreatic duct should not exceed ___
2mm
normal pancreatic measurements
- head and body: 2-3cm
- tail: 1-2cm
list vasculature adjacent to pancreas head
- rt lateral to SMV
- anterior to IVC
- Inf to PV
list vasculature adjacent to uncinate process
- post to SMV
- ant to aorta
list vasculature adjacent to pancreas neck
-anterior to portal confluence
list vasculature adjacent to pancreas body
-anterior to SMV, splenic vein and SMV
list vasculature adjacent to pancreas tail
splenic vein marks the posterior border of pancreatic tail
what are the two most common congenital anomalies of the pancreas
- pancreatic divisum
- annular pancreas
what is the most common congenital variant of the pancreas
pancreatic divisum
___: results from abnormal fusion of the pancreatic ducts during the embryologic development
pancreatic divisum
pancreatic dives results in what
shortened pancreas duct which only drains the head leading the accessory duct to drain the rest of the pancreas
pancreatic divisor increases the risk for what
pancreatic inflammation secondary to obstruction
___: results from the maldevelopment of the two embryologic elements of the pancreas
annular pancreas
annular pancreas may lead to what
duodenal obstruction
what happens with annular pancreas
the most ventral part of the pancreas encases the duodenum
___: inflammation of the pancreas secondary to the leakage of pancreatic enzymes from the acing cells into the parenchyma of the organ
acute pancreatitis
what is the most common cause of acute pancreatitis
alcohol abuse and biliary tract disease such as choledocholithiasis
what levels rise with acute pancreatitis
-amylase levels will rise within the first 72 hours lipase will also rise
what lab is most specific for diagnosing pancreatitis
lipase
___: peripancreatic fluid collection
phlegmon
where is one of the most common locations for a pancreatic pseudocyst
lesser sac
S/S acute pancreatitis
- elevated amylase and lipase
- leukocytosis
- elevated ALT and other liver function labs when biliary obstruction is present
- back pain
- fever
- n/v
S/A acute pancreatitis
- may appear normal
- diffusely enlarged hypoechoic pancreas
- focal hypoechoic area within pancreas
- peripancreatic fluid
- abscess formation may occur
- biliary obstruction may be present
- vascular complications may be seen
chronic pancreatitis is often caused by what
alcohol abuse
other than alcohol abuse what are some other causes of chronic pancreatitis
- hyperparathyroidism
- congenital anomalies
- genetic disorders
- pancreatic duct obstruction
- trauma
S/S chronic pancreatitis
- asymptomatic
- epigastric pain
- jaundice
- back pain
- possible elevation in amylase, lipasa, or ALP
- anorexia
- weight loss
- vomiting
- constipation
S/A chronic pancreatitis
- heterogenous or hyperechoic atrophic gland
- calcifications within gland
- pancreatic pseudocyst
- dilated pancreatic duct
- stones within duct may lead to obstruction
- possible portosplenic vein thrombosis
what is the most common primary pancreatic malignancy
pancreatic adenocarcinoma
pancreatic adenocarcinoma is the __ most common cancer related death in men
4th
where is the most common location for pancreatic adenocarcinoma
head
pancreatic adenocarcinoma will most often lead to what things?
- obstruction of CBD
- courvoisier GB
obstruction of both the CBD and the pancreatic duct is known as what
double duct sign
what is the surgical procedure that is performed on patients with pancreatic adenocarcinoma
Whipple procedure
describe what a Whipple procedure is
procedure that removes the head of the pancreas, the gallbladder, some of the bile ducts and the proximal duodenum
S/S pancreatic adenocarcinoma
- elevated amylase or lipase
- loss of appetite
- weight loss
- jaundice
- courvoisier GB
- epigastric pain
S/A pancreatic adenocarcinoma
- hypoechoic mass in head of pancreas
- double duct sign
- enlarged GB
cystadenoma within the pancreas may be referred to as either ___ or ___
- serous cystadenoma (microcytic)
- mucinous cystadenoma (macrocystic)
which has more malignant potential serous or mucinous cyst adenomas
mucinous
the malignant form of cystadenoma is termed ____
ctstadenocarcinoma
S/S cyst adenomas and cystadenocarcinomas
- may be asymptomatic
- epigastric pain
- weight loss
- palpable mass
- jaundice
S/S serous cystadenoma
- cystic mass
- may appear solid and echogenic secondary to the small size of the cyst
S/S mucinous cystadenoma and cystuadenocarcinoma
- multilocular cystic mass may contain mural nodules and calcifications
- may be associated dilated pancreatic duct
what are the two types of islet cell tumors
- insulinoma
- gastrinoma
islet cell tumors can either be ___ or ___
functional or non functional
___: excessive secretion of acid by the stomach that leads to peptic ulcers
Zollinger Ellison syndrome
functional insulimoas can cause what
hypoglycemia
S/S islet cell tumors
- insulinoma: low blood sugar symptoms
- gastrinoma: Zollinger Ellison syndrome
S/A islet cell tumors
- hypoechoic mass that may contain calcs
- small
- may be hyper vascular
true pancreatic cysts may be seen with what
- von hippel Lindau disease
- cystic fibrosis
- autosomal dominant PKD
S/S true pancreatic cyst
-possible history of von hippie Linda disease or CF, or ARPKD
S/A true pancreatic cyst
- well defined anechoic mass
- posterior enhancement
what are the two different types of transplant techniques
- exocrine bladder drainage
- exocrine enteric drainage
label the surrounding vasculature

- IVC
- RRA
- Aorta
- SMV
- SV
what pancreatic abnormality is shown here

annular pancreas
what pancreatic pathology is shown here

acute pancreatitis
what pancreatic pathology is shown here

chronic pancreatitis
what pancreatic pathology is shown in the head of the pancreas in this iamge

pancreatic adenocarcinoma
what pancreatic pathology is shown in these two images

islet cell tumors