the numbers Flashcards
neutropenia
ANC < 1500
lymphopenia
ALC < 1000
Neutropenia confirmed: if fever, then what?
take ANS: if < 500 mlâ> give IV antibiotics. Consider G-CSF
Neutropenia without history but is cyclic
probably an ELANE mutation (cyclic neutropenia)
Neutropenia with a history of neutropenia
ELANE mutation
isolated neutropenia â>
BM exam, morph, cytogenics, flow
neutrophilia
ANC (bands and polys) > 10,000
leukoerythroblastic rxn
leukocyte count > 50,000: w/addition of nucleated red cells and shistocytes on blood smear
lymphocytosis
absolute lymphocyte count > 5000
most common cause of lymphocyte count > 5000
CLL
infections producing lymphocytosis
infectious mono hepatitis CMV rubella pertussis TV Brucellosis syphilis
hydroxyurea
a myelsuppressive used to tx myeloproliferative disorders