peripheral t and NK neoplasms Flashcards
1
Q
what are they and what % of NHLs do they make up
A
heterogenous, 5-10%
2
Q
No ALK positivity
A
peripheral T cell lymphoma, unspecified
3
Q
ALK+, CD30+ neoplasm: most common age group is
A
anaplastic large cell lymphoma: young kids/children
4
Q
CD45
A
leukocyte common antigen (LCA): if + for this marker, we call it lymphoreticular.
5
Q
outcomes for peripheral T cell lymphomas unspecified
A
bad.
6
Q
presents as soft tissue masses with pruritis in children. what immunostains would be positive and what kind of cells would be seen?
A
anaplastic large cell lymphoma: alk +, uncommon, presents with ALK gene rearrangements on Chromosome 23
usually expressed CD30
very good prognosis
hallmark cells: horseshoe shaped nucleu and voluminous cytoplasm
7
Q
A
