lymphoma hubbard Flashcards
Signs and symptoms are largely those of cytopenias
bleeding and bruising due to decreased platelets
increased risk of infection due to neutropenia
macrocytosis
fatigue, weakness, and dyspnea due to decreased pro- duction of red blood cells.
Patients can have splenomegaly (25%).
MDS
very slow onset, chronic course. 1/2 of pts are still alive and have not required tx 6 yrs after dx
CLL
lymphoproliferative disorder evaluation
-peripheral blood lymphocyte flow cytometry
monosomy 5q
MDS
monosomy 7q
MDS
trisomy 8
MDS
8;21
AML
trisomy 12q
CLL
cd23+
CLL
8;14
burkitt
the quality of the lymph nodes in lymphoma
non tender and rubbery
lymph nodes become swollen and tender after drinking
hodgkins lymphoma
sweet’s syndrome
(AFND- acute febrile neutrophilic dermatosis)-
cutaneous manifestation of AML-bx shows myeloblasts in dermis-tx- management of AML