The Brain Stem Flashcards
group of cell bodies in the PNS
ganglion
groups of cell bodies in the CNS
nuclei
group of cell bodies on the surface of the brain
cortex
bundle of myelinated axons in the CNS connecting CNS structures
tract, fasiculus, column, pedundle, capsule, lemniscus
what are the 3 primary functions of the brainstem
Conduit: ascending (sensory) and descending (motor and autonomic) tracts
Cranial nerve ganglia and nuclei: sensory and motor for head, neck, viscera and hearing, equilibrium and taste
Reticular formation
what does reticular formation help in the regulation of
sleep, arousal, pain, perception, visceral activities, cardiovascular and pulmonary function
ALS
pain, crude touch, temperature
DCML
proprioception, vibration, discriminative touch
spinocerebellar tract
unconscious proprioception and coordination to cerebellum
what the primary descending tract
corticospinal tract (pyramidal tract)
where does the corticospinal tract go to
lower motor neurons in lamina 9 of the ventral horn of spinal cord
what descending tracts originate in the brainstem, are motor, but do not pass through the pyramids
extrapyramidal descending tracts
examples of extrapyramidal tracts
tectospinal, rubrospinal, reticulospinal, vestibulospinal, ceruleospinal and raphespinal tracts
connects CN 3, 4, and 6 with vestibular nuclei
medial longitudinal fasciculus
connects cortex to the brainstem
corticobulbar (corticobrainstem) tracts
bulb
brainstem
what two tracts cross in the brainstem
DCML (ascending) and corticospinal (descending) tracts
where is the crossing point in the brainstem
pyramids
what two CN are associated with midbrain
3 and 4
what 4 CN are associated with pons
5-8
what 3 CN are associated with medulla
9, 10, 12
where is CN 11 nuclei located
cervical spinal cord
netlike
reticulum
a neural network of reticular nuclei and axons extending t/o brainstem
reticular formation
where does reticular formation send information to (4 major regions of the brain)
thalamus, spinal cord, brain stem nuclei, cerebellum
what is the main function of the reticular formation
regulates the excitability of cortical neurons through many convergent and divergent synapses
what does the reticular formation process and regulate
- process sensory info
- regulate motor function
- regulate autonomic function
- regulate sleep/wake cycles and state of consciousness via Reticular Activating system
- regulate emotional behavior
ventral tegmental areas produces what
dopamine
pedunculopontine nucleus produces what
acetylcholine
raphe nucleis produces what
serotonin
locus coeruleus produces what
norepinephrine and epinephrine
motivation, decision making, reward seeking, drug addiction, schizophrenia
dopamine
influences movement through connections with basal ganglia and emotional system
acetycholine
in midline of medulla, pons and midbrain and is associated with mood, pain regulation and sleep
serotonin
under floor of 4th ventricle associated with direction of attention and regulation of autonomic functions
norepinephrine and epinephrine
what is the anterior division of brainstem and what is primarily there
basilar section, primary motor (descending tracts)
what is the posterior division of the brainstem
tegmentum
what is in the tegmentum
reticular formation, sensory nuclei an tracts, CN nuclei and medial longitudinal fasciculus
most inferior part of brainstem and continuous with spinal cord
medulla
location where most of the descending corticospinal tracts decussate
pyramids
where does the DCML synapse on
nucleus gracilis and nucleus cuteatus
what does DCML decussate to
medial lemniscus
what nuclei are found in medulla
spinal tract and nucleus trigeminal N
hypoglossal nucleus
MLF connecting CN 3, 4, 6 and vestibular nuclei
motor nucleus CN 10
solitary nucleus
nucleus ambiguus motor to CN 9 and 10
cochlear and vestibular nuclei CN 8
inferior olivary nucleus
nociception and temperature to the face
spinal tract and nucleus of trigeminal N
CN motor to the tongue
hypoglossal nucleus
coordination of eye movement with head movement
MLF connecting CN 3, 4, 6 and vestibular nuclei
gag and swallowing reflex, parasympathetic regulation
motor nucleus CN 10
visceral and taste from CN 7, 9, 10
solitary nucleus
motor to CN 9 and 10, vocal cords, pharynx, and swallowing
nucleus ambiguus
auditory, head position, VOR
cochlear and vestibular nuclei CN 8
motor information to cerebellum
inferior olivary nucleus
what are the function of medulla
coordinate cardiovascular control
breathing control
head movement
swallowing
tongue movement
SCM and upper trap function
gag reflex
continuous with medulla
pons
posterior pons borders what
4th ventricle
what does the anterior pons containg
descending motor tracts
what does posterior pons contain
ascending sensory tracts, MFL, reticular formation and autonomic pathways
what tracts synapse in the pons
corticopontine and corticobulbar tracts
what are the functions of pons
- process sensory info from face via CN 5
- control lateral eye movement via CN 6
- control facial and chewing muscles via CN 5 and 7
- process motor info from cerebrum and passes it to cerebellum
- conveys info about sound, head movements and head position via CN 8
uppermost part of brainstem
midbrain
what does the midbrain connect
diencephalon and pons
what connects midbrain to cerebellum and is the only way info can lead cerebellum
superior cerebellar peduncle
is within the midbrain and receives info from cerebral cortex and projects it to the spinal cord and cerebellum via rubospinal tract
red nucleus
part of CN 3 and constricts pupil and adjusts short of lens in eye
edinger-wesphal nucleus
pain suppression and coordination of fight or flight response
periaqueductal gray (PAG)
what are the two posterior collections of cell bodies that are important relay areas in the midbrain
superior and inferior colliculi
superior colliculi function
orients head/eyes toward external stimuli/movement
inferior colliculi function
relays auditory information to thalamus
involved in pupillary and accommodation reflexes of the eye
pretectal area
what are the functions of the midbrain
- eye movement, pupillary reflexes, shape of lens in eye
- coordination of somatic and autonomic response to nociception
- transmis efferent information from cerebellum to cerebral cortex
- regulation of muscle tone and distal UE extension
- relay of visual and auditory info to cortex
branches of the vertebral supply what
medulla
branches from basilar supply
pons and cerebellum
what artery supplies midbrain
posterior cerebral A
4 midline structures that begin with M
- Motor nuclei that move eyes (CN 3, 4, 6) and tongue (CN 12)
- Motor tract - corticospinal tract
- MLF - coordinates eyes with heat
- Medial lemniscus - DCML info to thalamus
4 lateral structures that begin with S
- Sympathetic tract that raises eyelids and pupillary dialator muscles
- Spinothalamic tract to thalamus
- Sensory tract of trigeminal N
- Spinocerebellar tract
4 CN in medulla
8, 9, 10, 12
4 CN in pons
5, 6, 7, 8
CN motor nuclei that innervate muscles divide equally into the number 12
3, 4, 6, 12
medial brainstem lesion affects
- 4 Ms
- motor nuclei depending on where the brainstem lesion is located
lateral brainstem lesion affects
- 4 Ss
- if in pons, affects CN 5, 6, 7, 8
- if in medulla, affects CN 8, 9, 10
cause a mix of ipsilateral and contralateral sx and interfere with vital functions and consciousness
brainstem lesions
do CN supply ipsilateral or contralateral face and neck
ipsilateral
do ascending and descending tracts supply ipsilateral or contralateral body
contralateral
what does a lesion in the lower medulla produce
- contralateral hemiplegia
- contralateral loss of proprioception, pressure, vibration, 2 point discrimination
- contralateral pain, temp, touch
- ipsilateral face, head, and neck paresis and paralysis
- may cause heart to stop beating, BP to fluctuate, and/or cessation of breathing
occurs with reticular formation or cortical lesions in hypothalamus, thalamus or cortex
disorders of consciousness
what can disorders of consciousness lead to
vegetative or minimally conscious state and locked in syndrome
brainstem tumors lead to increased what
intracranial pressure
sx/outcomes of brainstem lesions
HA, N and V, CN disorders, hydrocephalus
example of brainstem tumor that wraps around CN 8 that can cause tinnitus and deadness
acoustic neuroma
brainstem ischemia leads to abrupt onset of
dizziness, visual disorders, weakness, incoordination, somatosensory disorders
most common brainstem stroke and leads to blockage of PICA
lateral medullary/Wallenberg’s syndrome
second most common brainstem stroke that leads to blockage of AICA
lateral inferior pons
blockage of anterior spinal, vertebral, or basilar artery
medial medullary syndrome
occurs most often due to blockage of basilar A and affects medial structures
midbrain stroke
how to test for brainstem ischemia/stroke
VBI testing - neck ext/SB/rot
what are the 4 Ds of brainstem dysfunction
dysarthria, dysphagia, diplopia, dysmetria
difficulty swallowing - CN 5, 7, 9, 10, 12
dysphagia
double vision - CN 3
diploplia
difficulty speaking due to poor control of speech muscles
CN 5, 7, 10, 12
difficulty controlling distance of movements - cerebella
dysmetria
which CN are part of CNS
olfactory and CNS
sensory CN cell bodies in _____ outside the brainstem
ganglia
motor CN cell bodies in _____ inside the brainstem
nuclei
which CNs are myelinated by olgiodendrocytes
olfactory and optic