Tetracyclines (-cycline) Flashcards
1
Q
Example
A
Doxycycline
2
Q
MoA
A
30s subunit of bacterial ribosome
Antagonist
Inhibiting binding of aminoacyl-tRNA
3
Q
Indications
A
Alternative for COMMUNITY ACQUIRED pneumonia/cellulitis
Malaria
Fever
Lyme
4
Q
ADR
A
Chelates calcium --> Stains bones + teeth in young Hepatotoxic Blood disorders Agranulocytosis Blood dyscrasia Grey Baby Syndrome
5
Q
Prescribing Advice
A
X Pregnancy/Lactating or Children