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Antibiotics > Nitroimidazole > Flashcards

Nitroimidazole Flashcards

1
Q

Example

A

Metronidazole

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2
Q

MoA

A

Taken up by anaerobic bacteria/protozoa
Reduced to form reactive products
Deactivate cysteine-bearing enzymes
Makes DNA unstable when incorporated

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3
Q

Indications

A

C. difficile
Intra-abdominal sepsis
Intestinal protozoal disease

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4
Q

ADR

A 
Metallic taste
Dizziness/Headache
Hepatitis
Pancreatitis
Peripheral Neuropathy
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5
Q

Prescribing Advice

A

Reaction with Alcohol

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Antibiotics (13 decks)

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