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Antibiotics > Beta-lactam Monobactam > Flashcards

Beta-lactam Monobactam Flashcards

1
Q

Example

A

Aztreonam

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2
Q

MoA

A

Penicillin-binding protein
Antagonist = D-ala-D-ala
Inhibits transpeptidase enzyme activity
Prevents catalysis of NAMA-NAG peptide cross-linking during cell wall formation

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3
Q

Indications

A

Gram negative aerobic rods

e.g. Pseudomonas

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4
Q

ADR

A

GI Upset

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5
Q

Prescribing Advice

A

IV
Resistant to beta-lactamase
X Pregnancy

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Antibiotics (13 decks)

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