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Antibiotics > Beta-lactam Cephalosporins (cef-) > Flashcards

Beta-lactam Cephalosporins (cef-) Flashcards

1
Q

Examples

A

Cefuroxime
Cefotaxime
Ceftriaxone

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2
Q

MoA

A

Penicillin-binding protein
Antagonist
Inhibits transpeptidase enzyme activity
Preventing catalysis of NAMA-NAG peptide cross-linking during cell wall formation

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3
Q

Indications

A

Bacterial meningitis

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4
Q

ADR

A 
Nephrotoxicity
Alcohol intolerance
Hypersensitivity 
Stevens-Johnson's
Toxic epidermal necrolysis
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5
Q

Prescribing Advice

A

Parenteral

More susceptible to beta-lactamases

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Antibiotics (13 decks)

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