Beta-lactam Carbapenims (-penem) Flashcards
1
Q
Examples
A
Meropenem
Imipenem
2
Q
MoA
A
Penicillin-binding protein
Antagonist
Inhibits tranpeptidase enzyme activity
Prevent catalysis of NAMA-NAG peptide cross-linking during cell wall formation
3
Q
Indications
A
Severe resistant infection
Under ID guidance
4
Q
ADR
A
GI Upset
Hypersensitivity
Neurotoxicity
Renal Failure
CNS Disease
5
Q
Prescribing Advice
A
ID Guidance Only