Beta-lactam Penicillins (-cillin) Flashcards
1
Q
Examples
A
Benzylpenicillin
Flucloxacillin
Amoxicillin
Piperacillin
2
Q
MoA
A
Penicillin-binding protein
Inhibitor
Inhibits transpeptidase enzyme activity
Prevent catalysis of NAMA-NAG peptide cross-linking during cell wall formation
Inactivation of inhibitor of autolytic enzymes in cell wall
3
Q
Indications
A
Streptococci
Staphylococci
4
Q
ADR
A
Hypersensitivity, Anaphylaxis
Amoxicillin = otitis media, lyme
Encephalopathy
5
Q
Prescribing Advice
A
Combined with B-lacatamase inhibitors
Co-amoxiclav/Tazocin