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Antibiotics > Quinolones (-floxacin) > Flashcards

Quinolones (-floxacin) Flashcards

1
Q

Examples

A

Ciprofloxacin

Levofloxacin

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2
Q

MoA

A

Bacterial DNA gyrate (Topoisomerase II)
Antagonist
Prevents DNA double helix from becoming supercoiled
Prevents transcription + replication

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3
Q

Indications

A

Gram negative coliforms
UTI
Pseudomonas

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4
Q

ADR

A

Risk of C. difficile
GI
Hypersensitivity

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5
Q

Prescribing Advice

A

Caution in epilepsy
X Theophylline, NSAIDs
X Pregnancy

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Antibiotics (13 decks)

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