Macrolides (-ithromycin) Flashcards
1
Q
Examples
A
Erythromycin
Clarithromycin
Azithromycin
2
Q
MoA
A
50s subunit of bacterial ribosome
Antagonist
Prevents translocation of growing peptide chain
Inhibits bacterial synthesis
3
Q
Indications
A
ALTERNATIVE TO PENICILLIN
Pneumonia
4
Q
ADR
A
GI upset
Hypersensitivity reaction
QT Prolongation
5
Q
Prescribing Advice
A
Inhibits metabolism of Ciclosporin/Theophylline
CYP450 inhibitor