Macrolides (-ithromycin) Flashcards

1
Q

Examples

A

Erythromycin
Clarithromycin
Azithromycin

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2
Q

MoA

A

50s subunit of bacterial ribosome
Antagonist
Prevents translocation of growing peptide chain
Inhibits bacterial synthesis

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3
Q

Indications

A

ALTERNATIVE TO PENICILLIN

Pneumonia

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4
Q

ADR

A

GI upset
Hypersensitivity reaction
QT Prolongation

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5
Q

Prescribing Advice

A

Inhibits metabolism of Ciclosporin/Theophylline

CYP450 inhibitor

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