Glycopeptides Flashcards

1
Q

Examples

A

Vancomycin

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2
Q

MoA

A

Terminal moieties of NAMA + NAG protein
Antagonist
Prevents incorporation of NAMA + NAG subunits
Block elongation of peptidoglycan chains during cell wall formation
Specifically peptidoglycan cell wall

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3
Q

Indications

A

Severe Clostridium difficile (Oral)

MRSA (IV)

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4
Q

ADR

A

Rash
Ototoxicity
Nephrotoxicity

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5
Q

Prescribing Advice

A

Low oral bioavailability

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