Glycopeptides Flashcards
1
Q
Examples
A
Vancomycin
2
Q
MoA
A
Terminal moieties of NAMA + NAG protein
Antagonist
Prevents incorporation of NAMA + NAG subunits
Block elongation of peptidoglycan chains during cell wall formation
Specifically peptidoglycan cell wall
3
Q
Indications
A
Severe Clostridium difficile (Oral)
MRSA (IV)
4
Q
ADR
A
Rash
Ototoxicity
Nephrotoxicity
5
Q
Prescribing Advice
A
Low oral bioavailability