Test Two membrane structure Flashcards

1
Q

function of membrane

A

lipid bilayer of molecules, transport barrier, contains transport channels, flexible, expandable, and repairable

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2
Q

the lipid bilayer contains

A

phospholipids

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3
Q

what is amphipathic

A

membrane layer contains a polar and non polar portion

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4
Q

how is the lipid bilayer favorable

A

forms a ball to increase entropy

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5
Q

how is the lipid bilayer fluid

A

lipid molecules shift within the membrane, rotating and changing places

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6
Q

fluidity of the lipid bilayer depends upon

A

composition of lipid bilayer, packing of lipids by the length of the hydrocarbon tail and degree of saturation, environmental temperature

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7
Q

longer hydrocarbon tails mean what about fluidity

A

less fluidity

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8
Q

degree of saturation talks about what

A

number of hydrogen molecules around a carbon

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9
Q

saturated tails are

A

single bonds, contain more hydrogens and less fluid

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10
Q

unsaturated tails are

A

double bonds, fewer hydrogens, more fluidity, kinked

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11
Q

how does environmental temperature affect fluidity in lipid bilayer

A

affects length and saturation of hydrocarbon tails

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12
Q

what molecule prevents fluidity and enhances permeability barrier

A

cholesterol

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13
Q

what is the function of fluidity

A

cellular interactions, movement of proteins and lipids, fusion and division of membranes

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14
Q

what are the predominant phospholipids

A

phosphoatidylcholine, phosphoatidylethanolamine, phosphatidylserine, sphingomyelin

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15
Q

what are scramblases

A

enzyme that causes random movement of lipids from side to another to help equal out growth of bilayer

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16
Q

what are flippases

A

enzymes that cause specific movement of lipids

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17
Q

membrane synthesis occurs where

A

in the endoplasmic reticulum, lipids in SER and proteins in RER

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18
Q

how are glycolipids synthesized

A

so they face outside the cell

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19
Q

what is involved with glycolipid synthesis

A

transporting vesicles, no flippases

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20
Q

what do inositolphospholipids do

A

play a role in direction they are positioned

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21
Q

function of membrane proteins

A

membrane transport, anchors for stability, cell signaling receptors, enzymes for reactions

22
Q

what are transmembrane proteins

A

located through membrane, hydrophillic outside and hydrophobic inside

23
Q

what are membrane associated proteins

A

located in the cytosol only on half the bilayer,

24
Q

structure of membrane associated proteins

A

amphipathic alpha helix on surface of membrane

25
where are lipid linked proteins located
outside of the membrane except for the lipid group covalently anchored to membrane
26
what is the anchored lipid in lipid linked proteins
glycosylphosphatidylinositol (GPI)
27
how do protein attached proteins work
interact to non covalently with a membrane bound proteins and associates them with plasma membrane
28
which membrane proteins are intergral
transmembrane, monolayer associated, and lipid linked
29
which membrane proteins are peripheral
protein attached
30
how to isolate integral membrane proteins
destroy membrane with detergent to gain access to protein
31
how to isolate peripheral membrane proteins
membrane intact but remove protein with pH change
32
Describe transmembrane proteins with alpha helix
Span membrane, contain hydrophobic on outside and hydrophilic on inside
33
Single pass proteins use how many helices
One
34
Single alpha helices for single pass proteins are used for what
Cell signaling and receptors
35
Multi pass proteins use how many alpha helices
Several
36
Multi pass proteins with several alpha helices are used for
Pores
37
Transmembrane proteins using beta barrels are used for what
Structure and proteins
38
Cell membrane is strengthened by
Protein-attached proteins
39
What forms the cell cortex
Fibrous proteins such as spectrin
40
Purpose of spectrin
Strengthen the membrane on the cytosolic side and contains multiple binding sites
41
What is an example of a strong cell cortex
RBC, has strong cortex to create its shape
42
What is a way to restrict movement of membrane proteins
Membrane domains
43
What are some membrane domains
Tethers and diffusion barriers
44
What is glycocalyx
The cell coat
45
What are the carbohydrates on the cell surface
Glycoproteins and proteoglycans
46
Glycoproteins attach to what
Oligosaccharides
47
Are glycoproteins short or long
Short
48
Proteoglycans attach to what
Polysaccharides
49
Are proteoglycans short or long
Long
50
Function of carbohydrates on the cell surface
Protection from mechanical or chemical damage, lubrication to allow to slip into small or tight spaces, interaction with other cells, recognition