Test Two Energy Generation Flashcards
Function of carbohydrates for a cell
Fuel source and structural component
What is contained in the structural component of carbohydrates
Glycoproteins and glycolipids
What are the different types of carbohydrates
Polysaccharides, disaccharides, and monosaccharides
Example of polysaccharides
Starch, glycogen, fiber
Example of disaccharide
Sucrose, maltose and lactose
Example of monosaccharide
Glucose, galactose, and fructose
Liver converts what into glucose
Galactose and fructose
What is the digestion of carbohydrates
Breakdown of polysaccharides and disaccharides
Where does the breakdown of carbs occur
In GI then absorbed in the blood
Glucose diffuses from blood to where
Interstitial fluid through the cell membrane
Example of glucose diffusing into cells
Insulin
What organs don’t require insulin
Brain and liver
How does insulin enter into cell
Binds on channel with glucose allowing for insulin to enter
What enzymes are use to phosphorylate glucose and trap inside cell
Hexokinase and glucokinase
Where is hexokinase used
For all cells
Where is glucokinase used
Liver, kidney tubules and intestinal epithelium
Is hexokinase reversible or irreversible
Irreversible
Is glucokinase reversible or irreversible
Reversible
How does glucose exit the liver
Liver dephosphorylates glucose using glucose phosphatase to release it
What is the next step for glucose-6-phosphate
Can be oxidized to make ATP, stored as glycogen,
What is glycogenesis
Make glycogen
What is glycogenolysis
Break down glycogen to form glucose
Glycolysis starts with what
Glucose to fructose 1,6-bisphosphate
How much ATP is invested in glycolysis
2 ATP
What is the end product of glycolysis
Pyruvate
What is the total net ATP of glycolysis
2 ATP
If O2 is not available for pyruvate what occurs in human
Fermentation, pyruvate to lactate
What is needed for human fermentation
NAD+ and NADH
What is the new energy source in human fermentation
NADH
Lactate in cell diffuses where
Extracellular fluid in blood
When O2 is available what happens to lactic acid
Lactic acid is re converted into pyruvic acid
Where does lactic acid converting to pyruvic acid occur
Liver or heart
Fermentation in Yeast produces what end products
CO2 and ethanol
Before Kreb’s cycle occurs what needs to happen to pyruvate
Convert to acetyl-CoA
Kreb’s cycle only works when what is present
Oxygen
Acetyl CoA binds with what to create what
Oxaloacetate and creates citrate
What are the end products of Kreb’s cycle
3 NADH, 1 FADH2, 1 GTP per cycle
What is a byproduct of Kreb’s cycle
CO2
Function of mitochondria
Generate ATP
What disease occurs when mitochondria improperly functions
MERRT
Mitochondria can synthesize their own proteins and divide because
They have their own DNA and RNA
Where would you see a lot of mitochondria
Areas that need more ATP such as muscles or the heart
The matrix of mitochondria contains
Outer membrane and intermembrane space
Outer membrane of of matrix contains
Porins
The inner membrane in the mitochondria is known as
Cristae
The inner membrane of the mitochondria contains
Membrane transport proteins, electron transport and ATP synthesis
Where does oxidative phosphorylation occur
Mitochondria
first stage of oxidative phosphorylation
Electron proton gradient is formed, H+ flows down the electrochemical gradient and across the membrane
What is stage 2 of oxidative phosphorylation
ADP converts to ATP with ATP synthase
What is coupling in chemiosmotic coupling in oxidative phosphorylation
Electron transport, H+ pumping, and ATP synthesis
What is the role of oxygen in oxidative phosphorylation
Electrons combine with O2 and H+ to form
What is the final electron acceptor in oxidative phosphorylation
Oxygen
How many ATP for NADH
2.5
How many ATP for FADH2
1.5
The total oxidation of one glucose produces how many ATP
30
End product of glycolysis
2 pyruvate, 2 ATP and 2 NADH
End product of the citric acid cycle
6 NADH, 2FADH2 and 2 GTP
what is another pathway that metabolize glucose
pentose phosphate pathway and gluconeogenesis
what type of energy is produced through the pentose phosphate pathway
NADPH
what energy is used for the synthesis of fats
NADPH
excess glucose is stored as what
glycogen
when cell runs out of space, glycogen is converted to
fat in liver and adipose tissue
what provides the raw material for gluconeogenesis
glycerol, lactate, and several amino acids