Test Four Tissues And Cancer Flashcards

1
Q

Tissues form from

A

Cells joining together and extracellular matrix

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2
Q

Tissue maintenance consists of

A

Renewal and repair

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3
Q

What are cellulose fibers

A

Long fibers of polysaccharides

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4
Q

Cellulose fibers are formed by

A

Enzymes in plasma membrane interweaving into cell surface

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5
Q

Cellulose microfibrils guided by

A

Microtubules

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6
Q

Animal connective tissue

A

Tendons, bone and cartilage

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7
Q

Structure of collagen

A

Super helix, collagen fibrils that come together to make fibers

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8
Q

What makes collagen

A

Fibroblasts and osteoblasts

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9
Q

What is secreted by collagen fibrils with collagenase

A

Procollagen

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10
Q

Example of defect in collagenase

A

Ehlers Danlos Syndrome (stretchy skin)

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11
Q

How is collagen arranged

A

Secreted from cell and is put into place

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12
Q

What other components are in collagen

A

Fibronectin and integrins

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13
Q

Function of fibronectin in collagen

A

Grab collagen and bind to cell

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14
Q

Function of integrins in collagen

A

Bind to fibronectin and connect to cell

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15
Q

Function of proteoglycans

A

Link to GACs and resist compression, fills spaces and controls rate of water passage

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16
Q

Function of epi

A

Protective barrier, absorption, secretion and communication

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17
Q

Epi consists of

A

Apical and basal surface

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18
Q

Apical surface function

A

Absorbing, secreting and communication

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19
Q

Function of basal surface

A

Bind cells, anchors

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20
Q

Function of intestinal epi

A

Protective layer

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21
Q

Function of absorptive cells

A

Nutrients

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22
Q

Function of goblet cells

23
Q

Function of tight junctions

A

Tight seal, mechanical strength and communication

24
Q

What forms tight junctions

A

Claudins and occludins

25
Adherin junctions are held together by
Actin and form adhesion belt
26
Desmosome junctions are
Linking intermediate filaments through Cadheirns, link keratin together
27
Hemidesmosomes are
Link with intermediate filaments with integrins by anchoring to basal membrane
28
Cadherins are
Adaptors in between cells
29
Adherin junctions found where
Near top
30
Gap junctions have narrow gaps called
Connexons
31
Can gap junctions open and close
Yes
32
Function of gap junctions
Communication
33
Cell to cell adhesion uses
Desmosomes and actin bundles
34
Cell communication occurs
With cells around and gap junctions
35
Are nerve cells replaced
Nope
36
Intestinal epi replaced when
Every couple of days
37
Bone cells replaced
6 years
38
RBCs replaced every
120 days
39
Skin replaced every
2 months
40
Each stem cell can either
Differentiate or remain a daughter stem cell
41
What are hematopoietic stem cells
Potential cells to be anything
42
What cells can we turn into stem cells
Fat and bone cells
43
Causes of mutation
Inheritance, ionizing radiation, mutagens/ carcinogens, viruses
44
Example of preventable cancer
HPV and cervical
45
Somatic mutation
Cancer in mature body
46
Germ line mutation
Unborn situation
47
Damage mutation
Ionizing radiation, mutagen
48
Cancer properties
Enhanced cell proliferation, less of a response, no cell death, genetically unstable, invasive
49
Oncogenes
Genes that are mutated with dangerous result
50
Proto-oncogenes
Normal genes with potential
51
Tumor suppressor genes
Cancer critical genes
52
What causes colorectal cancer
Gene mutation and somatic mutation
53
What gene is missing in colorectal cancer
APC tumor suppressor gene
54
Treatments for cancer
Surgery, radioactive therapy, DNA destroying chemotherapy, choking blood supply, targeting cancer products, immunotherapy