Test Four Cell Cycle And Division Flashcards
In mammal, how long cell divide
1 hour
M phase contains both
Mitosis and cytokinesis
Mitosis is
The division of nucleus
Cytokinesis is
Division of cytoplasm
Interphase contains
S phase, G phases
S phase is
Synthesis and replication of nuclear DNA
what are the different types of G phases
G, G1, G2
The central control system of cell cycle helps
Regulate start of each phase
Central control system is regulated by
Feedback using check point
Purpose of G1 check point
Extracellular environment
G2 checkpoint
DNA damage repair
Mitotic checkpoint
Microtubules attached and occurs during middle of mitosis
Function of cyclins
Regulation cyclic machine by repeating activation/ inactivation of proteins
Cyclins turn off and on by
Binding/ releasing to cyclic dependent kinases
What dephosphorylates Cdks
Phosphatases
What pushes the cell into the S phase
S cyclins bind to S-Cdk and G1 cyclins binds to C1-Cdk
G1 cyclins binds to G1 Cdks to stimulate
Cell division
What targets the degredation of cyclin protein
Cyclical proteolysis
How are ubiquitin chains added to cyclins
Anaphase promoting complex (APC)
Cyclins are directed to proteosomes for destruction by
Ubiquitin chains attaching to cyclins
What stops or slows an unprepared cell before the cell cycle
Cdk inhibitors
Example of Cdk inhibitor
P27
What molecule promotes the cell cycle
Mitogens
How to stop the cell cycle
Destroying kinases
What binds to the origins of replication to start the S phase
ORC
ORC binds to what after binding to origin
Cdc6