Test Four Cell Cycle And Division Flashcards

1
Q

In mammal, how long cell divide

A

1 hour

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2
Q

M phase contains both

A

Mitosis and cytokinesis

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3
Q

Mitosis is

A

The division of nucleus

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4
Q

Cytokinesis is

A

Division of cytoplasm

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5
Q

Interphase contains

A

S phase, G phases

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6
Q

S phase is

A

Synthesis and replication of nuclear DNA

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7
Q

what are the different types of G phases

A

G, G1, G2

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8
Q

The central control system of cell cycle helps

A

Regulate start of each phase

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9
Q

Central control system is regulated by

A

Feedback using check point

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10
Q

Purpose of G1 check point

A

Extracellular environment

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11
Q

G2 checkpoint

A

DNA damage repair

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12
Q

Mitotic checkpoint

A

Microtubules attached and occurs during middle of mitosis

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13
Q

Function of cyclins

A

Regulation cyclic machine by repeating activation/ inactivation of proteins

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14
Q

Cyclins turn off and on by

A

Binding/ releasing to cyclic dependent kinases

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15
Q

What dephosphorylates Cdks

A

Phosphatases

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16
Q

What pushes the cell into the S phase

A

S cyclins bind to S-Cdk and G1 cyclins binds to C1-Cdk

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17
Q

G1 cyclins binds to G1 Cdks to stimulate

A

Cell division

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18
Q

What targets the degredation of cyclin protein

A

Cyclical proteolysis

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19
Q

How are ubiquitin chains added to cyclins

A

Anaphase promoting complex (APC)

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20
Q

Cyclins are directed to proteosomes for destruction by

A

Ubiquitin chains attaching to cyclins

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21
Q

What stops or slows an unprepared cell before the cell cycle

A

Cdk inhibitors

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22
Q

Example of Cdk inhibitor

A

P27

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23
Q

What molecule promotes the cell cycle

A

Mitogens

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24
Q

How to stop the cell cycle

A

Destroying kinases

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25
What binds to the origins of replication to start the S phase
ORC
26
ORC binds to what after binding to origin
Cdc6
27
Function of Cdc6
Causes other proteins to come together to form a pre-replicative complex and start DNA replication
28
What holds sister chromatids together
Cohesin rings
29
If DNA is damaged, what gene regulatory protein is activated
P53
30
Activation of p53 leads to transcription of
P21
31
P21 binds to
G1/S-Cdk and S-Cdk to stop cell cycle from continuing
32
M-Cdk triggers
Chromosome condensation and assembles mitotic spindle
33
What activates M-Cdk
M cyclin
34
How does M cyclin activate M-Cdk
Protein phosphatases that remove inhibitory phosphates
35
Condensins are
Help chromosomes condense by assembling around each chromatid
36
What separates chromosomes
Mitotic spindles
37
Cytokinesis involves what to divide cytoplasm
Contractile ring made up of myosin and actin
38
M phase consists of
Prophase, prometaphase, metaphase, anaphase, telophase and cytokinesis
39
How many centrosomes during mitosis
2 since one is replicated
40
When do centrosomes form asters or radial microtubules
Interphase and beginning mitosis
41
What part of mitotic spindle goes to plasma membrane
Positive end
42
What part of mitotic spindle goes toward centrosome
Negative end
43
Microtubule associated proteins (MAPs) bind and stabilize
Microtubules
44
During Mitosis, MAPs prevent stabilizing by
Being phosphorylated
45
What molecule shrinks microtubules
Catastrophins
46
Do plants have centrosome
Nope
47
What are centrosomes
Where microtubules grow out of
48
What occurs during prophase
Centrosomes move in different directions by microtubules pushing them apart
49
What occurs during prometaphase
Nuclear envelope disappears, microtubules bind to chromosomes
50
What part of microtubules grab center of chromosomes
Kinetochore microtubules
51
What are the three classes of microtubules in mitosis
Aster, kinetochore, and interpolar
52
Function of aster microtubules
Explores
53
Function of kinetochore microtubules
Bind to chromosomes
54
Function of interpolar microtubules
Control mitotic spindle
55
What occurs during metaphase
Chromosomes line up at equator and play tug of war
56
What occurs during anaphase
Sister chromatids pull apart by APC breaking cohesins
57
What separates cohesins
Separase
58
How to activate separase
Securin told by APC to release separase
59
What are the two stages of anaphase
A and B
60
What is anaphase A
Kinetochore microtubules pull apart chromosomes
61
What is anaphase B
Separate the centrosomes
62
What occurs during telophase
Daughter chromosomes separated and vesicles form around
63
What forms the nuclear lamina
Lamins are dephosphorylated
64
What makes the chromosomes decondense during telophase
Nuclear proteins
65
What organelles duplicate during mitosis
Mitochondria and chloroplasts
66
Organelles that don’t duplicated are separated by what for cytokinesis
Microtubules
67
The cleavage furrow forms during what mitotic stage
Anaphase