Test 5- Disinfectants, Alcohols and Aldehydes, Phenols, Idiophors, Chlorine Containing Compounds Flashcards
- Soaps
- Detergents
Disinfectants
Our most important cleaning agents. The utility as a disinfectant is limited, generally used before one is applied. Major action- aids in the mechanical destruction and removal of microbes.
- Usually made from fats and lye
- Depend on their alkalinity for cleaning action
- Grime and bacterial are suspended from the surface of an object and are washed off with H2O
- Combine with calcium and magnesium salts in hard water to form an insoluble scum.
- If followed by germicide, use 70% alcohol before the germicide is applied, because soap and some germicides combine to form inert compounds.
Soaps (Bar, Liquid, Granule or Impregnated Handy-Wipe Tissues)
A term used to distinguish synthetic compounds from soaps. Made from fats and oils by a complcated chemical process. As it is ionized in water, its electrically charged ions attach themselves to dirt and carry the dirt and microbes away with the rinse of water. Dissolve readily in cold water and completely in even the hardest water.
Detergents
Usually germicidial for pneumococci, streptococci, genococci, meningococcal and some influenza viruses. The hepatitis virus is unaffected.
Soaps and Detergents
- Isopropyl Alcohol
- Formaldehyde
- Glutaraldehyde
- cidex
- Di San
- Sporicidin
- Sonacide
- 3M brand disinfecting and sterilizing solution
Alcohols and Aldehydes
Superior to ethyl alcohol and is effective against vegatative bacilli (not spores). Effective in dilutions of 70% and stronger. It is not effective against hepatitis viruses but it does enhance the activity of other chemical agents such as the “quats” and chlorhexidine.
Isopropyl Alcohol
A gas which has excellent disinfective qualities against all bacteria, bacterial spores and viruses. When dissolved in water, it is called formalin. Mixtures of formalin, alcohol, and hexachlorophene make active germicidial solutions for sterilizing surgical and mortuary instruments, speedily killing bacteria, spores, and many viruses.
Formaldehyde
An aldehyde that is acidic in water. It is one of the latest and best additions to any disinfectant list. The action of the aldehyde is speeded up if the solution is alkalinized. Effective against the hepatitis virus. Exposure should be 10-12 hours for sterilization and 30 minutes for disinfection.
Glutaraldehyde
- Cidex
- Di San
- Sporicidin
- Sonacide
- 3M brand disinfecting and sterilizing solution
5 Examples of Glutaraldehyde
An alkaline solution of glutaraldehyde in 70% alcohol. It is an excellent bactericide, viricide, and sporocide. Excellent as a cold soak for instruments (Min-30 Minutes). Also may be used to soak linen and needles before non-incineration disposal. Hard on rubber and will etch plastic. Glutaraldehyde is a skin irritant and has been also classified as a carcinogen.
Cidex (Braind Name, Surgikos, Inc.)
A gluteraldehyde co-injection fluid. When alkinized with pHA- good clot dispersal (Brand name, Echoz Exco Co.), it is excellent for instruments (see label instructions). Most commonly used with cold water for instruments.
Di San (Brand Name, Champion Co.)
Brand name, Ayerst Labs - see cidex
Sporicidin
Brand name, Ayerst Labs- see cidex
Sonacide
Brand name, 3M co.- see cidex
3M Brand Disinfecting and Sterilizing Solution
- Amphyl
- Staphene
- O-Syl
- Hexachlorophene
- Phisohex
- Chlorhexidine
- Hibistat
- Hiblicens
Examples of Phenols
(Brand Name) A phenolic disinfectant containing a mixture of orthophenyl phenol, amylphenol, potassium ricinoleate, propylene glycol and alcohol. It is non-toxic and non-irritating to skin and mucous membranes. It is non-corrosive to metals and treated surfaces tend to retain anti-microbial action for several days. It can be mixed with soap and other antiseptics for use on skin and for other general cleaning purposes. It is lethal to fungi, many bacteria, and lipophilic viruses. It is lethal to herpes viruses.
Amphyl
(Brand name) A phenolic disinfectant containing a mixture of amylphenol, orthobenzylparachlorophenol and orthophenylphenol. Similar action as Amphyl.
Staphene
(Brand name, National labs) A phenolic disinfectant containing only orthophenylphenol. It is a germicide and fungicide. Similar action as Amphyl. An excellent general disinfectant for floors, tables, walls, etc. Not for use on hands and bodies.
O-Syl
A diphenol usually combined with detergents or incorporated into soaps. It is retained on the skin and leaves an anti-bacterial film. Some users may be allergic to hexachlorophene. It is not effective against Gram-Negative bacterial or spores; however, it is an excellent disinfectant when used against streptococcus and staphylcoccus.
- Example: Phisohex
Hexachorophene
(Brand name, Winthrup Labs)- A mixture of phisoderm (phisoderm is a detergent cream which is a mixture of wool fat, cholesterol, lactic acid and sulfonated petroleum). It is a more efficient cleaner than plain soap and hexachlorophene. It is a popular hand scrub because regular use gives maximal bactericidal effect and is non-irritating. It is not effective against Gram-negative bacteria or spores.
Phisohex (Example of Hexachlorophene)
A chemical antiseptic which is also a phenol derivative. This agent has the advantage of being active against Gram-negative organisms while possessing the prolonged action of hexachlorophene against staphylococci. Excellent hand and body disinfectant. Examples:
- Hibistat
- Hiblichens
Chlorhexidine
(Brand name, Stuart Pharmaceuticals) An antiseptic hand and body cleanser containing chlorhexidine gluconate. Used in surgery.
Hibistat (Chlorhexidine Example)
(Brand name, Stuart Pharmaceuticals) An antiseptic hand cleanser containing chlorhexidine gluconate.
Hiblicens (Chlorhexidine Example)
These represent a large group of compounds which act against many vegetative bacteria by attacking the cytoplasmic membrane. Widely used for the disinfection of clean inanimate objects. Many bacteria are resistant to these and they are easily inactivated by soaps, detergents, and organic materials. Their effectiveness and safety increase when they are combined with other disinfecting agents. New versions are being tested that don’t have some of the undesirable characteristics of the older group. They are not effective against hydrophilic viruses but are effective against lipophilic viruses.
Quaternary Ammonium Compounds (QUATS)
- Diaparine Chloride (Brand name)
- Zephiran Chloride
- Ceepryn Chloride
- Phemerol
Examples of QUATS
Brand Name. Example of a QUAT.
Diaparine Chloride
Brand name for Benzalkonium chloride, example of a QUAT.
Zephiran Chloride
Brand name for Cetylpyrdinium chloride, example of a QUAT.
Ceepryn Chloride
Brand name for Benzethonium chloride, example of a QUAT.
Phemerol
Compounds in which iodine is carried by a surface-active solvent. The free iodine liberated is the bactericidal agent. The surface-active solvent enhances the action of concentrations over 5000 parts per million.
Iodophors