Test 2: Protein supersecondary strucutres

Question 1

what structure is this called

Question 2

what is the domain in a protein

Answer 2

independent folding region that is associated with a certain function

Question 3

how are domains connected

Answer 3

weak interactions between side chains

Question 4

what do the interfaces in domains do

Answer 4

provide crevices and pockets for binding or catalytic sites

Question 5

what is an example of a domain

Answer 5

pyruvate kinase

Question 6

domains are important in what structure level

Answer 6

tertiary because they contain a hydrophobic core built from secondary structural units

Question 7

what are the 4 main protein classes

Answer 7

• alpha
• beta
• alpha+ beta
  -alpha/beta

Question 8

what classifies domains

Answer 8

their fold

Question 9

what is a fold

Answer 9

combination of secondary sturctures that form a core of a domain and the folds can have different motifs

Question 10

what is the EF- hand fold motif

Answer 10

• helix turn helix fold
• found in proteins that binds Ca+2

Question 11

what is the quaternary structure of a protein

Answer 11

organization of subunits in a protein with multiple subunits