etc part 1+ ox phos part 1 Flashcards

1
Q

where does etc and ox phos happen in euk.

A

inner mito membrane

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2
Q

where does oxphos and etc happen in prok

A

inner cell membrane

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3
Q

what energizes the etc

A

nadh and fadh2 made in glyc. pdh rxn and tca

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4
Q

where is more atp made

A

by ox phos

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5
Q

what is inner membrane impermeable to

A
  • most ions and molecules like H+
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6
Q

where are the high energy electron paris NADH2 and FADH2 transferred to

A

oxygen via etc

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7
Q

how is energy released in the mito used

A
  • used to pump protons into the intermembrane space to get charge separation
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8
Q

what is the mitochon known for

A

cellular batter

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9
Q

what drives atp synthase

A

electrochemical energy of protons falling back to matrix

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10
Q

what is the route of NADH in etc

A

Nadh > I> Q> 3> cyt c> 4> o2
produces 10H+

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11
Q

route of fadh2

A

fadh2>2>Q>3>cytc > 4> o2
6H+ out

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12
Q

what are the moble e- carriers

A

ubiqunione and cytochrome c

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13
Q

what is proton motive force

A

concentration gradient of H= across a membrane is harnessed to make atp

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14
Q

what complex has fmn redox coenzyme

A

1

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15
Q

coenzyme q is present in what complex

A

3

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16
Q

what does ubiquionene do

A

carries e= from complex I/II to complex 3

17
Q

what complex has the rieske iron sulfer center and q cycle

A

complex 3

18
Q

where does cytochrome c carry electrons

A

complex 3 to 4

19
Q

why us cytochrom c diff

A

peripheral membrane protein while other cytochromes are integral

20
Q

1 electron carrier needs how many cyt cs

A

2 cyt c ( 2 electrons from nadh)

21
Q

what is a protein w/ a heme posthetic group that is involved in e- transfer

A

cytochromes

22
Q

what does the heme fe alternate between

A

Fe+2 (ferrous) and Fe+3( ferric) states

23
Q

what happens to the coordination sites for the hemes in cytochrom

A
  • all 6 are occupied do not bind to O2
24
Q

what atom does complex 4 have

A

copper
cycle between reduced Cu+ (cuprous) and oxidized Cu+2 state cupric

25
Q

what cytochrome does complex 4 have

A

cyt a3 and binds and reduces O2 to water

26
Q

what complex has cytochrome bc1 comples, coQ cytochrom c reductase, cytochrome c-CoQ oxidreductase

A

3

27
Q

wht complex has cytochrome c oxidase

A

4

28
Q

succinate dh is what complex of etc

A

2

29
Q

what does complex 2 do

A

transfers e- directly to q skipping complex 1
- doesn’t directly contribute to pumpoing out of protons

30
Q

how did scientists disocer the order of the sequence of complexes

A

measured standard reduction potentials of all components - more positive the closer to O3

31
Q

how did scientists discover thre order of the sequence of complexes

A
  • look for intercting between complexes
  • inhibitors see which metabolites build up
32
Q

what happens with o2 consumption

A

stops an addition of an inhibitor