Tempus DPYD Flashcards
1
Q
What is pharmacogenetics?
A
How a single gene affects an individual’s response to medications.
2
Q
what is pharmacogenomics?
A
The study of how multiple genes affect an individuals response to medications.
3
Q
Alterations in DPYD can indicate toxicity to which drugs:
A
5-FU and Capecitabine
4
Q
What is 5-FU?
A
A common chemo drug used in treating breast and GI/Colorectal cancers.
5
Q
What’s the basics of this test?
A
- DPYD offering is an add-on to xT with tumor-normal match
- No additional tissue is required
- DNA germline-based NGS test, utilizes DNA from the normal match.
- 5 regions of DPYD gene analyzed
- This is a * germline* test
