Random cards (study)

Question 1

Walk me through the difference between germline and somatic variants:

Answer 1

Germline pathogenic variants are identified through blood or saliva. Somatic variants are detected by testing the tumor directly or through liquid biopsy to identify what DNA sequencing changes are promoting the tumor growth.

Question 2

Somatic cells, what are they?

Answer 2

All the cells of the body except the germline.

Question 3

Germline cells, what are they?

Answer 3

cells in the sexual organs that produce sperm and eggs.