T1DM - Mx principles

Question 1

Insulin therapy is indicated in all patients with TlDM that present below the age of
?, and all patients with T2DM that fail to respond to full medical treatment, or are
unsuitable for medical treatment

Answer 1

40

Question 2

TlDM management is similar in principle to T2DM management;

? care plan.
Structured ? programme.
---o DAFNE: dose-adjustment for ? ?.
Screen for complications.
o Less common in ? onset disease, as not enough ? to develop.
Monitor ? risk.

Answer 2

individual
education
normal eating
early
time
CV

Question 3

Lifestyle advice.
o Diet: ? counting is the most important advice, as taught in ?????.
o Advice for how to adjust diet/? for ? and consuming ?.
Insulin regimen.
o See below.
? review.

Answer 3

carb
DAFNE
insulin
exercise
alcohol
annual

Question 4

There are three types of insulin are available in the UK: ? insulin, human insulin ?, and ? insulin (rarely used).

–Human insulins are produced by recombinant ONA technology, and have the exact same ? ? sequence as human insulin.

Answer 4

human
analogues
animal
amino acid

Question 5

Human insulin analogues are produced in the same way as human insulins, but the insulin is modified to produce a specific desired kinetic characteristic, e.g. an ? duration of action or faster ?.

Answer 5

extended

absorption

Question 6

Animal insulins are extracted and purified from animal sources.
o These are no longer used, although some patients who have been on
them for a ? time may remain on them.

Answer 6

long

Question 7

Insulins are broadly categorized according to their ?-action profiles.

Answer 7

time