Conn's

Question 1

Most common in ? ? .
? ? leading to primary ?.
o Conn’s syndrome is responsible for primary ? in 60% of cases.
o ? adrenal ? is the second most common cause for primary hyperaldosteronism (30%).

Answer 1

young females
adrenal adenoma
hyperald
hyperald
bilateral
hyperplasia

Question 2

Hyper? leads to ? and ? retention.

Answer 2

ald
sodium
water

Question 3

Presentation;
o Mostly ?.
o ?.
• Resistant to treatment.
• May cause ?.
o Features of hypokalaemia.
• May cause ?, ?, tetany.
• May give ?.

Answer 3

aSx
HTN
headaches
cramps
weakness
polyuria

Question 4

Biochemical features;
o Hypokalaemia, with ? potassium loss.
o ? plasma ?:? ratio.
• Plasma aldosterone levels will not be ? by ? administration.

Answer 4

urinary
elevated
alb:renin
suppressed
fludrocortisone

Question 5

Further investigations;
o Once primary hyperaldosteronism is confirmed, ? ? is indicated to differentiate Conn’s from adrenal ?.
o Adrenal ? is an alternative method, where there is ? uptake of the isotope in ?.

Answer 5

adrenal CT
hyperplasia
scintography
unilteral
adenoma

Question 6

Management;
o ? adrenalectomy to remove the adenoma.
o ? pre-op to control ?/?
–this is trt of choice for ? ?

Answer 6

laparoscopic
spironolactone
htn/hypokal
bilateral hyperplasia