Insulin regimens

Question 1

Short Acting Insulins: aim to mimic the body’s insulin ? in response to ?.
? acting.
0 E.g. ?, Novarapid.
0 Injected with, or just ? food.
• Routine use ? food should be discouraged.
0 onset of action ? minutes.
0 Duration of action ?-? hours.

Answer 1

secretion
food
rapid
humalog
after
after
15
2-5

Question 2

Short-acting
Soluble insulin.
o E.g. ?, ? S.
o Generally injected ? minutes ? food.
o Onset of action ?-? minutes.
o Duration of action up to ? hours.

Answer 2

actrapid
humulin
30
before
30-60
8

Question 3

Intermediate-acting insulins: mimic ? insulin secretion.
E.g. ? I, lnsulatard.
- Onset of action ?-? hours.
Maximal effects between ?-? hours.
Duration of action up to ?-? hours

Answer 3

basal
humulin
1-2
4-12
16-35

Question 4

Long-acting insulins: mimic ? insulin secretion.
E.g. Lantus, ?, Tresiba, Detemir.
Used ?/? per day, and achieved a steady state level after ?-? days.

Various biphasic or mixed preparations also exist.
Combined long and short acting agents, e.g. ?.

Answer 4

basal
levemir
once/twice
2-4
novomix

Question 5

TlDM;

? ? regimens recommended.
o ? daily ?-acting insulin: Detemir.
o ? acting insulin with each meal: ?.
If this is not possible, ?-daily ? insulin regimens can be tried.
If the patient cannot achieve HbAlc %, insulin ? can be considered by a specialist team.

Answer 5

basal bolus
twice
long
short
novorapid
twice
mixed
8.5
pumps

Question 6

T2DM

Continue ? treatment to prevent excess weight ?.
? acting insulin injected once/ twice daily according to need.
? preparations can be used if patient’s HbAlc is particularly high

Answer 6

met
gain
intermediate
biphasic