Other Hypothalamic-Pituitary Disturbance

Question 1

Panhypopituitism;
Defective ? of all pituitary hormones.
Presentation;
o Fatigue, ?, ?-tension: GH / corticotropin deficiency.
o ? ?: ADH deficiency.
o ? : TSH deficiency

Answer 1

prod
myalgia
hypo
diabetes insipidus
hypothyroid

Question 2

Panhypopituitism;
Pituitary causes.
o Obliteration of pituitary by ?/? ?.
o ? ?/? of the pituitary.
o ? ? due to hypotensive shock

Answer 2

primary/met tumour
surgical removal/irradiation
ischaemic necrosis

Question 3

Panhypopituitism;
Hypothalamic causes.
o ? of the hypothalamus by;
-• Primary brain tumour: ?.
-• ?.
-• ?.
-• ?

Answer 3

destruction
craniopharyngioma
infection
infarction
sarcoid

Question 4

Panhypopituitism;
Diagnosis;
o ? hormones: low.
o ? gland hormones: low.
o Low response to ? tests.
o ? to localise the pathology.

Answer 4

pituitary
effector
stimulation
imaging

Question 5

Diseases of the neurohypothesis occur mainly as a result of damage to the
hypothalamus, e.g. ? invasion or ?.
Failure of ? production leads to diabetes insipidus, with ? and ?
Excessive ADH production leads to ?.

Answer 5

tumour
infarction
ADH
polyuria, polydipsia
SIADH