Systemic Lupus Erythematosus Flashcards
1
Q
define
A
chronic AI disease commonly affecting women in their 20-30s
2
Q
presentation
A
- Malar rash, discoid rash, photosensitivity, oral ulcers
- Fever, weight loss
- Renal disease
- Arthritis, pleuritis, pericarditis
- Haemolytic anaemia, leukopenia, thrombocytopenia
3
Q
what does lupus nephritis present with?
A
proteinuria and/or granular casts
4
Q
diagnosis
A
ANA, anti-dsDNA antibody, anti-Sm
raised inflammatory markers
low complement
urinarlysis
5
Q
management
A
immunosuppression
