Prostate Cancer Flashcards
who is this most common in?
black men
aged 70-74
FH
cadmium batteries
most common type
adenocarcinomas
metastatic sites
pelvic lymph nodes
bone
presentation
most asymptomatic
haematuria/ haematospermia
bone pain, anorexia, weight loss
diagnosis
DRE (peripheral zone cancers)
PSA
TRUS biopsy
bone scan, MRI, CT
causes of raised PSA
cancer BPH prostatitis UTI retention catheterisation DRE/PR large prostate bike rider
what MUST be done before PSA?
counselling
why do bad prognosis cancers not release PSA usually?
do not resemble cell of origin so do not release PSA
when is TRUS biopsy indicated?
abnormal DRE
elevated PSA
risks in TRUS biopsy
bleeding
sepsis
vaso-vagal fainting
grading of prostate cancer
Gleason score
staging of prostate cancer
TNM
TNM of organ-confined disease
T1-2, NO, MO
locally advanced TNM
T3-4, NO, MO
metastatic TNM
N+, M+