Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Respiratory Conditions (JBR) > Syndromes and other shit > Flashcards

Syndromes and other shit Flashcards

1
Q

What does SLE stand for?

A

Systemic lupus erythematosus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is SLEß

A

Multi-systemic autoimmune disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What occurs in SLE?

A

Autoantibodies are made against variety of auto antigens (anti-nuclear antibody)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How do SLE autoantibodies cause damage?

A

Immune complex deposition and complement activation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the clinical features of SLE?

A

ANA and DNA in 60% +ve
Malar rash in 50%
ESR raised but CRP normal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is ESR (blood test)?

A

Erythrocyte sedimentation rate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is Churg-Strauss Syndrome?

A

Triad of adult onset asthma, eosinophilia and vasculitis (vasospasm/MI/DVT)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Churg strauss affects which tissues?

A

Lungs
Heart
Skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What kind of syndrome may occur in Churg-Straussß

A

Systemic inflammatory response syndrome - glomerulonephritis especially if ANCA +ve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is ANCA?

A

Auto-neutrophil cytoplasmic autobody

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are investigation features of Churg-Strauss?

A

pANCA positive
Eosinophilic infiltrate
Granulomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is Caplan’s Syndrome?

A

Multiple lung nodules in coal workers with rheumatoid arthritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What causes Caplan’s syndrome?

A

Inflammatory reaction to anthracite (silica, asbestos)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is seen on CXR with Caplan’s Syndrome?

A

Bilateral peripheral nodule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is Goodpasteur’s Syndrome?

A

Acute glomerulonephritis and lung symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which lung symptom is associated with Good pasture’s syndrome?

A

Haemoptysis

17
Q

What is found histopathologically in Good-pasture’s syndrome?

A

Antiglomerular basement membrane antibodies

18
Q

What is found on CXR with Good Pasture’s syndrome?

A

Infiltrates due to pulmonary haemorrhage (lower zones)

19
Q

What is Wegener’s Granlomatosis?

A

Necrotising granulomatous inflammation and vasculitis of small and medium vessels

20
Q

What is seen on CXR with Wegener’s Granulomatosis?

A

Fluffly infiltrates of pulmonary haemorrhage

21
Q

What would be found in blood tests for Wegener’s Granulomatosis?

A

cANCA raised

Raised CRP/ESR

22
Q

Which characteristic rash is found in SLE?

A

Butterfly rash

23
Q

SLE predominantly affects?

A

Women

24
Q

Management of Wegener’s Granulomatosis requires?

A

Long term immunosuppression

25
Q

Wegener’s Granulomatosis has two components. Name these.

A

Granulomatosis

Polyangitis

26
Q

What is polyangitis?

A

Inflammation of multiple blood or lymph vessels

27
Q

What is the other term for Wegener’s Granulomatosis?

A

Granulomatosis with Polyangitis (GPA)

28
Q

What does ACOS stand for?

A

Asthma COPD Overlying Syndrome

29
Q

What is ACOS?

A

COPD with eosinophilia

Respiratory Conditions (JBR) (26 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions