Surrénales Flashcards

1
Q

Localisation

A

x

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2
Q

Irrigué par

A

x

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3
Q

Tissu

A

x

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4
Q

Deux zones

A

x

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5
Q

Les stéroïdes surrénaliens

Concentration

A

x

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6
Q

Liposolubilité

A

x

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7
Q

Sécrétion

A

x

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8
Q

Fixation protéine

A

x

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9
Q

Fraction qui diffuse dans les cellules

A

x

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10
Q

Biosynthèse

A

x

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11
Q

Biotransformation

A

x

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12
Q

Les stéroïdes surrénaliens

MA

A

x

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13
Q

STRUCTURE
Combien de cycle
Combien de cycle de 6C
Combien de cycle de 5C

A

x

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14
Q

C27

A

x

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15
Q

C21

A

x

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16
Q

C19

A

x

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17
Q

C18

A

x

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18
Q
Double liason = 
Quel endroit (2)
A

x

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19
Q

CONFGURATION SPATIALE
Propriété de?
Trans
Cis

Principalement trans ou cis?

A

x

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20
Q

Stéroïdogénèse

Précurseur

A

x

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21
Q

Stéroïdogénèse

Stockage

A

x

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22
Q

Stéroïdogénèse

Enzyme

A

x

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23
Q

Stéroïdogénèse
Étape limitante à quel endroit?
Qu’est-ce qui se passe

A

x

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24
Q

Stéroïdogénèse

RE microsome

A

x

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25
Q

Stéroïdogénèse

Mitochondrie

A

x

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26
Q

Stéroïdogénèse

Cortisol diffusion

A

x

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27
Q

Stéroïdogénèse

Si besoin augmente?

A

x

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28
Q

Anatomie

Localisation

A

x

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29
Q

Anatomie

Zone la plus importante

A

x

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30
Q

Anatomie

Origine

A

x

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31
Q

Anatomie

Volume

A

x

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32
Q

Glomérulée

Localisation

A

x

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33
Q

Glomérulée

Sécrétion (1)

A

x

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34
Q

Glomérulée

CYP

A

x

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35
Q

Aldostérone

Rôle (2)

A

x

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36
Q

Aldostérone

Localisation (4)

A

x

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37
Q

Aldostérone

Effet long terme

A

x

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38
Q

Aldostérone

Effet court terme

A

x

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39
Q

Aldostérone

Régulation par (5)

A

x

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40
Q

Aldostérone

Liaison protéine

A

x

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41
Q

Aldostérone

Demi-vie

A

x

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42
Q

Aldostérone

Métabolisme

A

x

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43
Q

Aldostérone
Synthèse
Étape limitante

A

x

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44
Q

Aldostérone

Étape 1

A

x

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45
Q

Aldostérone

Étape 2

A

x

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46
Q

Aldostérone

Étape 3

A

x

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47
Q

Aldostérone

Étape 4

48
Q
Fasciculée
Riche en (3)
49
Q

Fasciculée

Sécrétion (3)

50
Q

Fasciculée

CYP (2)

51
Q
Fasciculée
Augmentation par (2)
52
Q

Fasciculée

Stockage

53
Q

Fasciculée

Type de sécrétion (3)

54
Q

Fasciculée

pic

55
Q

Fasciculée

Creux

56
Q

Fasciculée

Effet rapide

57
Q

Fasciculée

Effet moyen

58
Q

Fasciculée

Effet lent

59
Q

Effets (10)

60
Q

Effet SNC

61
Q

Effet

Rein

62
Q

Effet foetus

63
Q

Effet os

64
Q

Effet muscle

65
Q

Effet cardio

66
Q

Effet immunosuppression

67
Q

Effet anti-inflammatoire

68
Q

Effet neutrophile

69
Q

Effet lymphocyte B

70
Q

Liaison à (2)

71
Q

Type 2

72
Q

Type 1

73
Q

RÉGULATION

74
Q

Stimulation par

75
Q

Inhibition par

76
Q

Atrophie surrénalienne

77
Q

Insuffisance surrénalienne

78
Q

Infusion d’ACTH

79
Q

SYNTHÈSE

Essentiel (2)

80
Q

SYNTHÈSE

Étape limitante

81
Q

SYNTHÈSE

Étape 1

82
Q

SYNTHÈSE

Étape 2

83
Q

SYNTHÈSE
Étape 3
a)
b)

84
Q
MÉTABOLISME
Liaison plasmatique (2)
85
Q

MÉTABOLISME

Excrétion journalière

86
Q

MÉTABOLISME

Conversion en cortisone

87
Q

MÉTABOLISME

17-H-CS

88
Q

Réticulée

Localisation

89
Q

Réticulée

Sécrétion

90
Q

Réticulée

Hormones (4)

91
Q

Réticulée

Activité

92
Q

Réticulée

Androstènediol

93
Q

Réticulée

Rôle (3)

94
Q

RÉGULATION

Fonction de

95
Q

RÉGULATION

Production androgène chez la femme

96
Q

RÉGULATION

Production ménopause surrénale

97
Q

RÉGULATION

Production androgène chez l’homme

98
Q

RÉGULATION

Métabolisme

99
Q

RÉGULATION

DHEA-S

100
Q

SYNTHÈSE

101
Q

Cholestérol + SCC =>

102
Q

Pregnenolone + 17A-H =>

103
Q

17A-H-Pregnenolone + 17-20 Lyase

104
Q

DHEA + 17B-HSD =>

105
Q

DHEA + 3B-HSD =>

106
Q

Médullosurrénale

Localisation

107
Q

Médullosurrénale

Type de cellule

108
Q

Médullosurrénale

Cytoplasme riche en

109
Q

Médullosurrénale

Entre les cellules (2)

110
Q

Médullosurrénale

Origine

111
Q

Médullosurrénale

Volume

112
Q

Médullosurrénale

Hormones (2)

113
Q

Adrénaline

114
Q

Noradrénaline

115
Q

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Agit où?
Amplifie quoi?