Suger Qs Flashcards

1
Q

What passes through the inguinal canal in males and females?

A

spermatid cord / round ligament of the uterus / ilioinguinal nerve (only through part)

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2
Q

Components of the spermatic cord

A

3 coverings – external, cremasteric, internal spermatic fascia

3 arteries – testicular artery , artery of the vas, cremasteric artery

3 veins – testicular vein, vein of the vas, cremasteric vein

3 nerves – ilio-inguinal (skin sensation anterior 1/3 external genitalia), genitofemoral (to cremaster muscle),
sympathetic (vas and testicular pain)

3 others - Vas deferens, lymphatics, tunical vaginalis

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3
Q

Describe contents of sperm

A

60% seminal / 30% prostate / 10% sperm

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4
Q

3 narrow parts of ureter

A
  • pelvis of kidney

- crossing common iliac -entrance into bladder

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5
Q

Name the branches of the lumbar plexus

A
I Twice Get Laid On Fridays 
ilioinguinal
iliohypogastric
genitofemoral
lateral cutaneous obturator L2-4
 femoral L2-4
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6
Q

A man presents with increased urge, frequency of urination and small amounts of semen in the urine. What nerve has been affected and why?

A

hypogastric sympathetic affected - internal urethral sphincter affected therefore semen goes into bladder & no receptive relaxation of detrusor muscle

In males internal involuntary - detrusor & external voluntary - urethral muscle - prevents semen passing into bladder

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7
Q

3 parts of pelvic bone
-where do they fuse

give three differences in pelvic diaphragm

A

ilium/Ishcial/pubic
=acetabulum

males have more acute angle
women have smaller pelvic inlet
males have ischial spines

female = lighter, smoother, thinner. tilted forward

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8
Q

Muscles of pelvis diaphragm

A

Levator ani = iliococcygeus & pubococcyegeus/coccygeus

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9
Q

What is the equation for GFR

average speed?

A

GFR = Kf (Pgc - Pbs) - (πgc)

  • 125ml/min
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10
Q

What factors affect ability to cross glomerular filtrate barrier?

-features of creatinine (£)

A

Pressure
Size / charge of molecule
Rate of blood flow
Binding to plasma proteins

-creatinine - freely filtered, not secreted / reabsorbed, not metabolised

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11
Q

Define renal clearance

A

Volume of plasma from which a substance is completely removed by the kidney per unit time (min)

Clerance of S = (urine (S) X volume of urine ) / plasma (S)

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12
Q

What is henderson-hasselbalch equation?

A

pH = 6.1 + log([A-] / [HA])

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13
Q

Most common secondary messenger?

A

cAMP

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14
Q

Name 3 embryological kidneys - which germ layer? Which persists?

A

pronephros, mesenophros, metenephros

  • metenephros remains
  • intermediate mesoderm
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15
Q

What must be removed from pronsulin to produce active insulin?

A

C-peptide

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16
Q

Describe hormone levels during pregnancy

A
  1. GnRH released from hypothalamus
  2. FSH & LH released from AP
  3. FSH causes maturation of primary follicles
  4. Follicles begin to secrete oestrogen
  5. Graafian follicle forms and other atrophy
  6. Graafian secretes higher levels of oestrogen - LH
    inhibited
  7. Oestrogen levels rise until high levels cause LH surge
  8. LH surge causes ovulation and formation of corpus
    luteum
  9. Oestrogen levels fall and then are restored by corpus
    luteum - proliferation of uterine lining & smooth muscle
  10. Progesterone levels also rise (corpus luteum) -
    increases vascularity of uterine lining & inhibits uterine
    contraction
  11. Corpus luteum not sustained causing fall in oe & pro =
    menstruation
17
Q

Blood flow to outer 2/3 cortex of kidney

-Three types of acute kidney injury?

A

peritubular network

i) Pre-renal // low bp, heart failure, liver cirrhosis, diarrhoea decreased blood flow to kidney
ii) Renal // glomerulonephritis damage to kidney
iii) Post-renal // stones, obstructed catheter urinary tract obstruction

18
Q

Bladder nervous supply

A

SNS - hypogastric (T12 - L2) internal sphincter & detrusor receptive relaxer PNS - pelvic splanchnic (S2 - S4) contraction of detrusor
Somatic - pudendal (S2-S4) external sphincter