Succinylcholine

Question 1

Brand Name

Answer 1

Anectine

Question 2

Drug Class

Answer 2

Deporlarizing Neuromuscular Paralytic

Question 3

Mechanism of Action

Answer 3

Binds with cholinergic receptors @ motor end plate of neuromuscular junctions
Produces a phase 1 block manifested by fasiculations

Question 4

Indications

Answer 4

Rapid sequence intubation (RSI)

Question 5

Contraindications

Answer 5

Acute narrow angle glaucoma, penetrating eye injuries, malignant hyperthermia, burns, extensive muscle injury. Any expected complications associated with airway management

Question 6

Adverse Effects

Answer 6

Apnea, tachycardia, bradycardia, prolonged muscle rigidity, increased occular pressure, rhabdomyolysis, cardiac arrest

Question 7

Precautions

Answer 7

Oxytocin, beta blockers, and organophosphates

May potentiate effects, diazepam can reduce duration of action

Question 8

Dose and Administration

Answer 8

1-1.5mg/kg (adults and pediatrics)

Onset: 1 min, peak 1-3 mins, duration: 5-10 mins