Mannitol Flashcards

1
Q

Brand Name

A

Osmitrol

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2
Q

Drug Class

A

Osmotic Diuretic

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3
Q

Mechanism of Action

A

Decrease cerebral edema and intracranial pressure

Promotes urinary excretion of toxins

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4
Q

Indications

A

Cerebral edema, increased ICP, rhabdomyolysis, blood transfusion reactions

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5
Q

Contraindications

A

Hypotension, pulmonary edema, severe dehydration, CHF, active intracranial bleed

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6
Q

Precautions

A

May precipitate digitalis toxicity

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7
Q

Adverse Effects

A

H/A, confusion, seizures, pulmonary edema, tachycardia, CP, CHF, hypotension, N/V, dehydration

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8
Q

Dose and Administration

A

0.5-1.0g/kg IVP over 5-10 minutes

Infusion of 0.25-2g/kg over 4-6 hours prn

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