Morphine

Question 1

Brand Name

Answer 1

Roxanol, M.S. Contin

Question 2

Drug Class

Answer 2

Opioid Analgesic

Question 3

Mechanism of Action

Answer 3

Agonist for opioid receptor sites, suppresses fear and anxiety centers of brain, increases peripheral venous capacity, decreases preload and afterload, decreases cardiac O2 demand

Question 4

Contraindications

Answer 4

head injury, exacerbation of COPD, decreased LOC, hypovolemia, pt on MAOI’s in past 14 days

Question 5

Adverse Effects

Answer 5

Confusion, sedation, H/A, CNS depression, resp depression, apnea, syncope, bradycardia, tachycardia, N/V, dry mouth

Question 6

Precautions

Answer 6

Potentiates sedative effects of phenothiazine’s, CNS depressants may potentiate effects, MAOI’s may cause paradoxical excitation

Question 7

Dose and Administration

Answer 7

Adult: 2-4mg slow IVP (med. direction)
Pedi: 0.1-0.2mg/kg IV, IO,IM, SQ

Question 8

Indications

Answer 8

Pain control, CHF, pulmonary edema, cardiac related CP