Magnesium Sulfate Flashcards

1
Q

Brand Name

A

Magnesium Sulfate

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2
Q

Drug Class

A

Electrolyte

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3
Q

Mechanism of Action

A

Depresses CNS, controls seizures by blocking ACh, @ myoneural junction
Smooth muscle relaxant in bronchospasm and uterine contractions
Stabilizes cardiac myocyte in torsades

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4
Q

Indications

A

Torsades, eclampsia, premature labor contractions, bronchoconstriction ta is refractory to beta 2 agonist tx

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5
Q

Contraindications

A

Heart blocks, myocardial damage

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6
Q

Adverse Effects

A

Drowsiness, CNS depression, respiratory depression, atrioventricular blocks, hypotension, vasodilation, hyperflexia

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7
Q

Precautions

A

May enhance effects of other CNS depressants

Changes in cardiac function seen with cardiac glycosides

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8
Q

Dose and Admistration

A

Eclamptic seizures: 1-4g over 3 mins.
Torsades: 1-2g IV (infusion rate 5-60 mins depending on stability)
Asthma: 25-50mg/kg infusion over 15-30 minutes

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