Hydroxocobalamin Flashcards

1
Q

Brand Name

A

Cyanokit

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2
Q

Drug Class

A

Antidote

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3
Q

Mechanism of Action

A

Binds directly to cyanide forming cyanocobalamin (Vitamin B12) which is readily excreted

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4
Q

Indications

A

Known or suspected cyanide poisoning

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5
Q

Contraindications

A

None

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6
Q

Adverse Effects

A

HTN, allergic rxn have been reported, N/V, dyspnea, indigestion, dizziness, bright red skin pigmentation that can last several days

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7
Q

Precautions

A

Not compatible in same IV line w/ many other medications

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8
Q

Dose and Administration

A

5g IV infusion @ 15mL/minute over 15 mins
May repeat one time
Pedi: 70mg/kg, same infusion rate

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