Dopmaine

Question 1

Brand Name

Answer 1

Inotropin

Question 2

Drug Class

Answer 2

Sympathomimetic

Question 3

Mechanism of Action

Answer 3

Dilates renal vasculature (low dose)
Increases HR, force of contraction, and speed of impulses (mid dose)
Constricts peripheral vasculature (high dose)

Question 4

Indications

Answer 4

Cardiogenic shock, septic shock, distributive shock, symptomatic bradycardia

Question 5

Contraindications

Answer 5

Hypovolemic shock, pheochromocytoma (adrenal tumor with increased catecholamine release), tachydysrhythmias, V-fib

Question 6

Adverse Effects

Answer 6

H/A, anxiety, dyspnea, dysrhythmias, HTN, palpitations, CP, increased myocardial O2 demand, PVC’s, N/V

Question 7

Precautions

Answer 7

Incompatible with alkaline solutions, MAOI’s and Bretylium will enhance effects, beta blockers will antagonize effects. Do not give with Phenytoin (hypotension, bradycardia, seizures)

Question 8

Dose and Adminstration

Answer 8

2-20mg/kg/min titrate to effect
2-5mcg/kg/min (low dose)
5-15mcg/kg/min (mid dose)
15-20mcg/kg/min (high dose)