substance abuse- exam 3 Flashcards

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1
Q

What is a substance use disorder

A
  • there is a pattern of use/unable to quit
  • Causes the individual problems.
  • Physiological changes
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2
Q

What is the DSM 5 criteria for substance use disorders (including the ones for pattern of use/impaired control, social impairment, risky use, and pharmacological criteria)

A

Pattern of use develops because of impaired control, as evidenced by:
- Taken in larger amounts and or over longer. than intended.
- Tries unsuccessfully to quit
- Increased time acquiring using or recovering from substance.
- Intense craving for the substance
Causes the individual problems significant social impairment or distress:
- use disrupts commitments at work, school or home.
- Social, occupational, recreational, activities given up
- Social and interpersonal problems, including verbal or physical fights
Causes the individual problems involves risky or hazardous use:
- Use in situations which are physically dangerous. For example, DWI
- Legal problems, including substance related arrests
- Worsening physical or psychological problems.
- Failure to abstain despite these difficulties.
Evidence of the body’s physiology has changed:
- Tolerance and withdrawal

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3
Q

What is withdrawal

A

Symptoms, including negative physiological and psychological reactions occur in absence of the substance; and/or the substance is taken to avoid symptoms

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4
Q

What are delirium tremens?

A

Caused by sudden drop in blood alcohol content in a chronic alcohol drinker, and includes hand trimmer, hallucinations, increased sweating and seizures

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5
Q

What are the different types of tolerance? And how do they work

A

Increased liver enzymes (inducible)
receptor down regulation or inactivation
learned or homeostatic tolerance

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6
Q

What are depressants

A

Slows down functioning
effects GABA (brains brake)
Inhibits
Keeps neurons from sending signals

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7
Q

What neurotransmitter system do depressants act on?

A

Slows the functions of the central nervous system, slow body functions- GABA

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8
Q

What are the overdose of symptoms for barbiturates, benzos, and alcohol

A
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9
Q

What is the CNS action of depressants

A

Slows the central nervous system by inhibiting the neurons and keeping them from firing.

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10
Q

What are the initial behavioral side effects of alcohol

A

It is stimulating reduces, reduces tension stress; relaxes inhibitions

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11
Q

What are the later effects with larger doses of alcohol

A

loss of motor coordination, sedation, and sleep.

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12
Q

What kind of drug is alcohol? And how does it work in the CNS

A

Alcohol is a depressant and it and it inhibits the neurons from firing. It slows the central nervous system

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13
Q

How does the body get rid of alcohol/primarily by the action of which organ

A

Alcohol is absorbed directly into the blood and metabolized by the liver, using inducible enzymes

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14
Q

define binge

A

5 drinks in a row for men, 4 drinks in a row for women.
A drink is 12 ounces of beer, 5 ounces of wine, or 1 1/2 ounces of hard liquor.

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15
Q

Define polydrug use

A
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16
Q

What is FASD

A

Fetal alcohol syndrome disorder

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17
Q

What is cirrhosis

A
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18
Q

What is AA, who runs AA, and what are the 12 steps

A
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19
Q

What happens to the GABA receptor when depressants are used

A
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20
Q

What are synergistic effects and cross tolerance?

A
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21
Q

Which neurotransmitter systems do stimulants work on

A
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22
Q

What are stimulants

A
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23
Q

What are the specific mechanisms of action for cocaine and amphetamine

A
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24
Q

What are the signs and symptoms of a potential overdose on stimulants?

A
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25
Q

What are the medical uses of stimulants

A
26
Q

What are several things amphetamines can be used for

A
27
Q

What are opiates and narcotics medically used for

A
28
Q

What are some examples of opiates and narcotics

A
29
Q

What neurotransmitter system does opiates and narcotics work on

A
30
Q

What are signs and symptoms of an overdose on opiates/narcotics

A
31
Q

What are signs of withdrawal from opiates/narcotics

A
32
Q

What is methadone and what is narcan? And what are they used for

A
33
Q

What are hallucinogens

A
34
Q

What is the name of the plant marijuana comes from

A
35
Q

What is the active ingredient in marijuana? And what receptor does it bind to

A
36
Q

What are the therapeutic/medical effects of marijuana

A
37
Q

What are effects marijuana can have on sleep? And hormones secretion

A
38
Q

What is hassish and marinol

A
39
Q

What are benefits and problems of smoking as the route of administration for hallucinogens

A
40
Q

What are entourage compounds

A
41
Q

What is CBD?

A
42
Q

What is retrograde synaptic transmission

A
43
Q

What is PCP and what are the signs and symptoms of someone on it?

A
44
Q

What is MDMA

A
45
Q

What are substance-induced disorders

A
46
Q

What are treatments for substance abuse

A
47
Q

What is reward craving

A
48
Q

What is relief craving

A
49
Q

What is detox and how does it work?

A
50
Q

What is disulfuram

A
51
Q

What is naltrexone

A
52
Q

What other addiction is included in this group in the DSM 5?

A
53
Q

What are the two theoretical areas of dysfunction in the brain, causing the inability to control use?

A
54
Q

What is a Blum’s Reward Deficiency syndrome

A
55
Q

What does blums reward deficiency syndrome have to do with the nucleus/accumbens and pleasure center, MFB, brain stem/VTA, D2 receptors

A
56
Q

Who was James Olds, Kenneth Blum?

A
57
Q

What is EBS

A
58
Q

What normally triggers the reward system

A
59
Q

Which neurotransmitter is released in the nucleus accumbens when we experience reward? How do humans describe this?

A
60
Q

What puts an individual at risk for substance abuse disorders

A