Stuff to know from immune slides Flashcards
what is empiric therapy
abx therapy given before culture results
what is definitive therapy
abx given after culture results
what is prophylactic antibiotic therapy
preventative abx given before surgery
what is superinfection
abx eliminate or reduce normal flora, causing overgrowth of other bacteria or fungi
cause of pseudomembranous colitis or C. diff
abx disrupt normal gut flora creating overgrowth of c.diff
what does release of histamine in the body do
increase HR
vasodilation -> decreased BP
bronchoconstriction
increased gastric acid -> N&V
what does epinephrine help with
vasopressor (increase BP)
dilate airways
increase heart ability to pump blood
alpha/beta adrenergic agonists (receptor)
what are the requirements for SIRS (systemic inflamatory response syndrome)
Temp: <96.8 to >100.4F
Resp rate: >20
Heart rate: >90
WBC: > 12,000 or <4,000 &
>10% neutrophile bands
abnormal neutrophil range and band
50-70% normal >70% abnormal
0-8% normal >10% band abnormal
when to give antipyretic
> 102F
what conditions would the pt considered to be in sepsis
2 SIRS requirements
confirmed or suspect active infection
what condition is considered to be severe sepsis
confirmed sepsis, signs of end organ damage
Hypotension 120/80 normal (<90)
Lactate >4 mmol
what is considered septic shock
severe sepsis with persistent signs of end organ damage, hypotension, lactate >4 mmol
what does qSOFA score tell you
screen the likelihood of a pt having sepsis
list infections that are most commonly associated with sepsis
pneumonia
GI infections
kidney, bladder, urinary system infections
bacteremia (bloodstream infection)
