Hypertension Meds Flashcards
what do ACE inhibitor names end in
“pril”
pharm action of ACE inhibitors
block production of angiotensin II which is used for aldosterone & ADH;
leading to increased output of water & Na
adverse effects of ACE inhibitors
- persistent dry cough
- hyperkalemia
- severe hypotension first dose
- rash/metallic taste in mouth
contraindication for ACE inhibitors
- teratogenic
- liver dx
- hypotension
what do ARBs names end in
“sartan”
ACE inhibitors vs. ARBs
ARBs is second choice as it doesn’t protect acute MI
adverse reactions for ARBs
- angioedema
- headache, dizziness,
what do you use to treat angioedema
epinephrine
contraindications for ARBs
- teratogenic
- kids younger than 6yrs old
what to be aware of for ACE inhibitors and ARBs
Avoid pregnancy
Angioedema
Cough
Elevated K (5+)
No green leafy vegetables
Careful for hypotension after first dose
list examples of aldosterone antagonists
eplerenone (inspra)
adverse effect of eplerenone
hyperkalemia
contraindication of eplerenone
- hyperkalemia
- lactation
- increased creatinine
name 1 direct renin inhibitors
aliskiren (Tekturna)
how does aliskiren work
binds with renin which inactivates angiotensin I
