DM drugs important stuff Flashcards
sulfonylureas
adverse effects:
hypoglycemia
GI issues, constipation
contraindicated:
pregnancy, lactation, DKA
meglitinides
adverse effects: similar to sulfonylureas
hypoglycemia
drug for renal insufficiency
biguanides
adverse effects:
metallic taste
vit. B12 deficiencies
contraindicated:
renal/hepatic issues, severe infection
hold 48hrs before invasive procedure
thiazolidinediones (TZDs) (glitazones)
adverse effects:
fluid retention
hepatotoxic
decrease oral contraceptive effectiveness
contraindicated:
heart issues, hypertension
alpha- glucosidase inhibitors
adverse effects:
GI ISSUES
contraindicated:
IBS, GI obstruction etc.
gliptins (DPP-4 inhibitors)
adverse effects:
pancreatitis, angioedema
monitor blood amylase, kidney panel
incretin mimetics
adverse effects:
GI issues, renal failure, pancreatitis
contraindications:
renal issue, pregnancy (teratogenic)
amylin mimetics
contraindications:
poor insulin regimen adherence
stuff that slow GI motility
which insulins are rapid acting
aspart
glulisine
lispro (Humalog)
which insulins are long-acting
detemir (Levemir)
glargine (Lantus)
peak time of short acting insulins
1-1.5hrs
peak time of regular insulin
2-3hrs
intermediate insulin peak time
5-8hrs
long-acting insulin peak time
no peak
which insulins are basal insulins
NPH
long acting - glargine (lantus), detemir
which insulin can be given IV
regular goes right in the vein
which insulin can’t be mixed
long means “lonely”
order of mixing NPH and regular insulin
clear to cloudy
“you are Not Retired, you are a R N”
