Antiseizure Meds Flashcards
phenobarbital MOA
enhances GABA (calming effect/ block transmission) neurotransmitter
side effects of phenobarbital
sedation, dizziness, cognitive impairment, potential for dependence
phenytoin (Dilantin) MOA
block voltage gated Na channels to reduce abnormal electrical activity
phenytoin side effects
hirsutism
gingival hyperplasia
narrow therapeutic window
name 2 benzodiazepines
lorazepam
diazepam
benzodiazepines MOA
enhance GABA to increase inhibitory neurotransmission
diazepam side effect
watch for respiratory depression
general side effects of benzodiazepines
sedation, drowsiness, ataxia ( no coordination), and risk of tolerance and dependence long term
acute seizure meds
phenobarbital
phenytoin
benzodiazepines (lorazepam, diazepam)
carbamazepine MOA
block Na channels to reduce abnormal electrical activity
side effects of carbamazepines
drowsiness, dizziness, nausea
aplastic anemia, agranulocytosis (regular blood monitoring required)
depakote side effects
weight gain, tremor, GI upset, liver/pancreas toxic
gabapentin side effects
dizziness, peripheral edema
