CAD meds

Question 1

what drug classification is Atorvastatin (Lipitor)

Answer 1

HMG-CoA reductase inhibitor

Question 2

pham action of statins

Answer 2

increase HDL
decrease LDL/VLDL & total cholesterol by inhibiting HMG CoA reductase (enzyme that makes cholesterol in the liver)

Question 3

adverse drug reactions of statins

Answer 3

myopathy - pain in muscles that can lead to rhabdomyolysis (breakdown of muscle protein that can lead to kidney damage)

hepatotoxicity

Question 4

what to monitor for statins

Answer 4

CK if muscle pain
liver function tests

Question 5

contraindications of statins

Answer 5

teratogenic
liver dx
young kids

Question 6

what drug classification is gemfibrozil, fenofibrate, or fenofibric acid

Answer 6

fibrate

Question 7

pharm action of fibrates

Answer 7

increase HDL
mod decrease of LDL/VLDLs

Question 8

adverse drug reaction of

Answer 8

Gi issues
Gallstones
Myopathy
hepatotoxicity

Question 9

contraindications for fibrates

Answer 9

gall bladder dx
liver dysfxn
severe renal impairement

Question 10

pharm action of nitroglycerin

Answer 10

vascular smooth muscle dilation

venous dilation of cardiac preload which decreases force required to contract

decreases oxygen demand of heart

relax angina spasms

Question 11

adverse effects of nitroglycerin

Answer 11

headaches
orthostatic hypotension
tachycardia
tolerance

Question 12

contraindications for nitroglycerin

Answer 12

teratogenic
increased cranial pressure
severe anemia
constrictive pericarditis
uncorrected hypovolemia

Question 13

pharm action of Na channel blockers

Answer 13

slow down electric signals
reduce transition of pain signals

Question 14

what are classification of quinidine and procainamide

Answer 14

sodium channel blockers

Question 15

adverse effects of quinidine & procainamide

Answer 15

GI issues
tachycardia
hypotension
widen QRS and prolonged QT
shock with rapid infusion
lupus with long-term therapy
cinchonism (tinnitus, visual, headache, N&V)

Question 16

contraindications with sodium channel blockers

Answer 16

severe heart block (slow pulse)
torsades de pointes dysrhythmia (twisting of points on ECG)

Question 17

what class is lidocaine

Answer 17

sodium channel blocker

Question 18

adverse drug reaction of lidocaine

Answer 18

CNS
hypotension, bradycardia, heart block in high doses

Question 19

contraindications for lidocaine

Answer 19

supraventricular dysrhythmias
untreated bradycardia/heart block

Question 20

what class do flecainide and propafenone go

Answer 20

sodium channel blockers

Question 21

nitroglycerin when to give sublingual PO or patch

Answer 21

PO for stable and predicable
patch for unstable and random

Question 22

when to call 911 on nitroglycerine

Answer 22

pain after 5 mins 1st dose
max dose 3 in 5 mins intervals

Question 23

function of statins

Answer 23

lower bad lipids
increase good lipids HDL
reduce likelihood of MI

Question 24

side effects of statins

Answer 24

STAT accronym
S: sore muscles
T: toxic liver
A: avoid grapefruit & St. John’s wort
T: take at night

Question 25

contraindications for statins

Answer 25

teratogenic
liver dx
renal d/o

Question 26

4 steps when someone has MI

Answer 26

oxygen
aspirin
nitroglycerin IV
morphine to relax heart and decrease workload

in order

Question 27

what meds to give post MI

Answer 27

heparin drip
nitroglycerin IV drip
Beta blockers
Ca channel blockers