STIs

Question 1

Impact of STIs x3

Answer 1

Infertility
Vertical transmission
Risk of cervical cancer

Question 2

Risk factors of STIs x5

Answer 2

Age<25
Hx of STI
Immunosuppression
Multiple sexual partners
Alcohol and substance abuse

Question 3

Describe chlamydia trochomatis x2

Answer 3

Gram negative, obligate intracellular organism

Question 4

The -itis of chlamydia x3 and management

Answer 4

Urethritis, cervicitis, salpingitis
Erythromycin 500mg QID x7/7

Question 5

2 effects of doxycycline on fetus, 1 effect on mother

Answer 5

Musculoskeletal and dental defects
Hepatotoxicity

Question 6

Causative organism of lymphogranuloma venereum and the serotypes

Answer 6

Chlamydia trachomatis L1-L3

Question 7

Characteristic features of primary and secondary lymphogranuloma venereum

Answer 7

1- painless ulcer that heals spontaneously
2- painful swelling that may rupture

Question 8

Gram negative diplococcus bacterium

Answer 8

Neisseria gonorrhea

Question 9

Clinical presentation of gonococcal urethritis x3

Answer 9

Dysuria, increased frequency
Purulent, blood tinged discharge

Question 10

Extragenital manifestations of gonorrhea x4

Answer 10

Pharyngitis
Arthritis
Arthritis dermatitis syndrome
Gonococcal proctitis

Question 11

Treatment of uncomplicated, complicated and disseminated gonorrhea (3)

Answer 11

Uncomplicated- ceftriaxone IM single dose
Complicated- ceftriaxone IM, DCN PO x14/7
Disseminated- ceftriaxone IV every 24hrs x7/7

Question 12

Gram negative spiral shaped spirochete bacteria

Answer 12

Syphilis

Question 13

Describe 4 stages of syphilis

Answer 13

1. Chancre
2. Maculopapular rash
3. Condylomata lata
4. Gumma

Question 14

4 treponemal tests

Answer 14

FTA ABS- fluorescent treponema antibody absorption test
TPPA- Particle agglutination
TPHA- Hemagglutination assay
IgG/IgM immunoassay

Question 15

Describe the jarisch herxheimer reaction

Answer 15

Inflammatory response> flu like symptoms due to death of treponemas within 24hrs of starting treatment

Question 16

5 adverse outcomes of syphilis in pregnancy

Answer 16

Miscarriage
Prematurity
Still birth
Congenital infection
Perinatal death

Question 17

USS findings of syphilis infected fetus x7

Answer 17

IUGR
Ascites
Hydrops
Microcephaly
Polyhydramnios
Placentomegaly
Hepatosplenomegaly

Question 18

Medical mgt of syphilis in pregnant women x2

Answer 18

Benzathine penicillin 2.4MU IM weekly x3 doses
if allergic give Erythromycin 500mg PO QID x14/7

Question 19

Causative agent of granuloma inguinale and treatment

Answer 19

Klensiella granulomatis
Azithromycin

Question 20

Gram negative encapsulated falcutative anerobe

Answer 20

Klebsiella granulomatis

Question 21

Where are Donovan bodies found

Answer 21

Granuloma inguinale

Question 22

Aerobic non motile Protozoan with flagella

Answer 22

Trichomonas vaginalis

Question 23

3 stages of genital herpes

Answer 23

Prodromal stage
Vesicular stage
Ulcerative stage