Infections in Pregnancy Flashcards
How does fetus acquire syphilis x2
Vertical transmission
Transplacental
Adverse effects of congenital syphilis x3
Miscarriage
Preterm birth
Perinatal death
Neonatal features of congenital syphilis x5
Sabre shins
Saddle nose
Mulberry molars
Hutchinson’s teeth
Eighth nerve deafness
2 specific syphilis tests
FTA abs tests
TPI- T.pallidum immobilization test
Medical management of syphilis, dosing and duration
Benzyl penicillin 2.4MU IM once weekly, 3 doses
Maternal complications of Group B strep x3
Preterm labour
Prolonged ROM
Intrapartum fever
Medical management of group B strep x2 + dosing, timing
Ampicilin 2g stat, 1g 4 hourly
Benzyl penicillin 3g stat, 1,5 hourly
Congenital anomalies of rubella x5
Cataract
Glaucoma
Deafness
Heart disease
Microcephaly
Fetal manifestations of CMV x3
IUGR
Microcephaly
Chorioretinitis
Medical management of CMV
Ganciclovir
Which HSV causes neonatal infections
HSV2
Fetal manifestation of HSV x4
IUGR
Prematurity
Hydrocephalus
Microcephaly
Indications for CS in HSV x2
Primary attack within 6weeks
Mother with genital lesions
Methods of transmission of varicella zoster virus x3
Direct contact with vesicles
Air borne transmission
Infected secretions from nasopharynx
How vesicles appear in VZV x4
Macules> papules > vesicles > crusted papules
Maternal complications of VZV x5
Varicella pneumonia
Adrenal insufficiency
Glomerulonephritis
Encephalitis
Arthritis
USS findings suggestive of congenital varicella syndrome x5
IUGR
Hydrops
Microcephaly
Cardiac malformations
Limb deformities
Management of Varicella ZV infection
Acyclovir 8000mg PO x5/7
Postpose delivery until a week after rash onset
Management of chronic hepatitis
Lamivudine 100mg OD
Factors affecting initiation of hep b treatment x4
Presence of cirrhosis
HBe antigen
HBe antibodies
ALT > 2xupper limit
Prevention of neonatal hep b infection x2
Hep b immunoglobulin
Hep b vaccine
Purpose of cotrimoxazole in HIV positive women
Infection prevention, malaria prophylaxis
Medical management of baby born to HIV mother x2
Nevirapine syrup up to 6wks
Cotrimoxazole from 6wks+
Toxoplasmosis triad
Chorioretinits
Hydrocephalus
Toxoplasmosis
Management of toxoplasmosis x3
Spiramycin
Sulfadiazine
Pyrimethamine
Describe parameters for UTI x2
> 100 000 organisms/ml if asymptomatic
100 organisms/ml with pyuria if symptomatic
Prophylaxis for UTI x2
Nitrofurantoin
Cephalexin