stimulants Flashcards

1
Q

Compared to modafinil, methylphenidate is _______ effective for the treatment of ADHD, and ________ effective for the treatment of narcolepsy

A

equally; more

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1
Q

Methamphetamine is made from amphetamine by substituting a ________ group.

A

-CH3

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2
Q

Methylphenidate blocks the reuptake of

A

DA & NE

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3
Q

What is the pharmacodynamic mechanism of methylphenidate?

A

Blocks DA reuptake, increases DA release, stimulates DA receptors

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4
Q

An important target area in the brain for the therapeutic effects of methylphenidate is the

A

prefrontal cortex

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5
Q

Methamphetamine produces anorexigenic effects by

A

creasing CART production in the hypothalamus

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6
Q

The major pharmacodynamic mechanism of amphetamine is

A

increased release of neurotransmitters

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7
Q

A drug that has the same effect as adrenaline is known as a

A

sympathomimetic

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8
Q

serious side effects of methamphetamine use?

A

rhabdomyolysis
cardiac arrest
hyperthermia

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9
Q

Cocaine is used medically as

A

an anesthetic

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10
Q

drugs that are sympathomimetic work in the _______ and mimic the effect of ___________

A

PNS ; mimic the effect of adrenaline

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11
Q

formication is …..

A

the feeling of insects crawling on one’s body or under one’s skin

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12
Q

sibutramine (meridia) has a primary indication for …..

A

obesity

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13
Q

provigil (modafinil) has a primary indication for…. (3)

A

Narcolepsy, shift-work sleep disorder, sleep apnea

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14
Q

methamphetamine (trade name)

A

Desoxyn

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15
Q

methylphenidate (trade name) / mechanism of action

A

Ritalin

inhibits reuptake of DA & NE

16
Q

MDMA (class of drug)

A

hallucinogen & stimulant

17
Q

lisdexamfetamine (trade name)

A

vyvanse

18
Q

modafinil (trade name) / use

A

Provigil

Narcolepsy, shift-work sleep disorder, sleep apnea

19
Q

The excretion rate of methamphetamine is dependent upon

A

urine pH

20
Q

The peripheral side effects of psychostimulants resemble activation of the

A

sympathetic NS

21
Q

The therapeutic uses(s) of amphetamine is/are:

A

Treatment of both narcolepsy and ADHD

22
Q

An important target area in the brain for the therapeutic effects of methylphenidate is the

A

prefrontal cortex

23
Q

The primary indication of sibutramine is the treatment of

A

obesity

24
Q

Methamphetamine produces anorexigenic effects by

A

Increasing CART production in the hypothalamus