psychedelics Flashcards
scopolamine is a _________
ACh antagonist
scopolamine can sometimes be found in…..
motion sickness medications
enactogens work as……
DA, NE, and 5HT agonists
myristicin & elemicin is found in……
nutmeg & mace
methlyated amphetamines: potency / toxicity?
very potent, highly toxic
SE of MDMA?
-Hyperthermia
-Bruxism (teeth grinding)
MDMA is __________
sympathomimetic
how does MDMA work?
Increases release of DA, NE, 5-HT via reuptake mechanism
ketamine is used as a pediatric anesthetic because….
no BP / respiratory effects
ketamine may be used medically for….
-Pediatric anesthesia
-Asthma/COPD
-Topical application for nerve pain
-Emergency surgery in field conditions in war zones
dectromethorphan is a _______ derivative (& how does it work?)
opiate;
-Antagonist of NMDA
-Antagonist at certain nicotinic receptors
-Blocks nicotine addiction
Increases 5-HT release
ketamine has a _____ half life
short (2.5-3hrs)
LSD
DMT
psilocybin
The psychedelic whose action does not directly involve serotonin, dopamine, or acetylcholine neurons is:
PCP
The catecholaminelike psychedelics have major effects on the following neurotransmitters:
serotonin and dopamine & NE
List a few serotoninlike psychedelics?
LSD
bufotenine
DMT
What is the legal status of peyote in the U.S.?
It is protected under the Religious Freedom Restoration Act for use by members of the Native American Church
The molecular structure of LSD is very similar to that of
serotonin
LSD has been studied as a treatment for all of the following (3)
depression
anxiety
PTSD
The NMDA antagonist class of psychedelics was initially developed as
anesthetics
What is the psychedelic class of mescaline?
enactogen
LSD is derived from
ergot
PCP is a(n) ….
((mechanism of action))
glutamate antagonist
categories of psychedelics: (5)
Anticholinergic
Catecholaminelike
Serotoninlike
Glutamatergic
Opioid
natural sources of scopolamine
belladonna, datura, mandrake, moonflower
adverse effects of scopolamine
hyperthermia, tachycardia, hypertension
what is an enactogen? ( & name a few)
a catecholaminelike psychedelic; has combined stimulant and psychedelic effects
DA, NE, & 5HT agonists
mescaline, myristicin, elemicin, MDMA
what are 2 NDMA antagonists
PCP, ketamine
ketamine is a schedule ____ drug
3
NDMA antagonists are also referred to as ….
dissociative anesthetics
What is the psychedelic class of mescaline?
enactogen
PCP is a/n
Glutamate antagonist
