psychedelics

Question 1

scopolamine is a _________

Answer 1

ACh antagonist

Question 2

scopolamine can sometimes be found in…..

Answer 2

motion sickness medications

Question 3

enactogens work as……

Answer 3

DA, NE, and 5HT agonists

Question 4

myristicin & elemicin is found in……

Answer 4

nutmeg & mace

Question 5

methlyated amphetamines: potency / toxicity?

Answer 5

very potent, highly toxic

Question 6

SE of MDMA?

Answer 6

-Hyperthermia
-Bruxism (teeth grinding)

Question 7

MDMA is __________

Answer 7

sympathomimetic

Question 8

how does MDMA work?

Answer 8

Increases release of DA, NE, 5-HT via reuptake mechanism

Question 9

ketamine is used as a pediatric anesthetic because….

Answer 9

no BP / respiratory effects

Question 10

ketamine may be used medically for….

Answer 10

-Pediatric anesthesia
-Asthma/COPD
-Topical application for nerve pain
-Emergency surgery in field conditions in war zones

Question 11

dectromethorphan is a _______ derivative (& how does it work?)

Answer 11

opiate;

-Antagonist of NMDA
-Antagonist at certain nicotinic receptors
-Blocks nicotine addiction
Increases 5-HT release

Question 11

ketamine has a _____ half life

Answer 11

short (2.5-3hrs)

Question 12

LSD

Question 13

DMT

Question 14

psilocybin

Question 15

The psychedelic whose action does not directly involve serotonin, dopamine, or acetylcholine neurons is:

Answer 15

PCP

Question 16

The catecholaminelike psychedelics have major effects on the following neurotransmitters:

Answer 16

serotonin and dopamine & NE

Question 17

List a few serotoninlike psychedelics?

Answer 17

LSD
bufotenine
DMT

Question 18

What is the legal status of peyote in the U.S.?

Answer 18

It is protected under the Religious Freedom Restoration Act for use by members of the Native American Church

Question 19

The molecular structure of LSD is very similar to that of

Answer 19

serotonin

Question 20

LSD has been studied as a treatment for all of the following (3)

Answer 20

depression
anxiety
PTSD

Question 21

The NMDA antagonist class of psychedelics was initially developed as

Answer 21

anesthetics

Question 22

What is the psychedelic class of mescaline?

Answer 22

enactogen

Question 23

LSD is derived from

Answer 23

ergot

Question 24

PCP is a(n) ….
((mechanism of action))

Answer 24

glutamate antagonist

Question 25

categories of psychedelics: (5)

Answer 25

Anticholinergic
Catecholaminelike
Serotoninlike
Glutamatergic
Opioid

Question 26

natural sources of scopolamine

Answer 26

belladonna, datura, mandrake, moonflower

Question 27

adverse effects of scopolamine

Answer 27

hyperthermia, tachycardia, hypertension

Question 28

what is an enactogen? ( & name a few)

Answer 28

a catecholaminelike psychedelic; has combined stimulant and psychedelic effects

DA, NE, & 5HT agonists

mescaline, myristicin, elemicin, MDMA

Question 29

what are 2 NDMA antagonists

Answer 29

PCP, ketamine

Question 30

ketamine is a schedule ____ drug

Answer 30

3

Question 31

NDMA antagonists are also referred to as ….

Answer 31

dissociative anesthetics

Question 32

What is the psychedelic class of mescaline?

Answer 32

enactogen

Question 33

PCP is a/n

Answer 33

Glutamate antagonist