drug abuse Flashcards

1
Q

Drug vaccines, such as NicVax, are probably most effective at

A

preventing addiction

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2
Q

The biological definition of addiction states that addictive substances

A

activate the VTA pathway

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3
Q

The mesolimbic pathway is made up of neurons that produce

A

dopamine

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4
Q

The mesolimbic pathways begins in the VTA and terminates in the

A

nucleus accumbens, amygdala, and prefrontal cortex

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5
Q

The use of clonidine to treat alcohol/opiate addiction is an example of which pharmaceutical treatment strategy?

A

withdrawal maintainence

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6
Q

Administration of Methadone to heroin addicts is an example of

A

agonist substitution

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7
Q

The reason antagonist administration strategies are often unsuccessful is due to

A

patient non-compliance

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8
Q

What proportion of patients addicted to alcohol/drugs have also been diagnosed with a psychiatric disease?

A

1/3

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9
Q

The following are all advantages of the partial-agonist substitution pharmacological approach

A
  • dec w/d sx
    -does not induce abuse
    -reduces cravings
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10
Q

Stress impacts addiction in all of the following ways

A

-stress and addiction share similar neurobiological pathways
-stress increases the likelihood of substance abuse
-stress increases the likelihood of craving and relapse

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11
Q

The “Rat Park” experiments, by Bruce Alexander, demonstrated that addiction rates are powerfully determined by

A

Social and environmental factors

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12
Q

The use of Chantix to help people stop using nicotine is an example of what kind of pharmaceutical approach?

A

Partial agonist substitution

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