drug abuse Flashcards
Drug vaccines, such as NicVax, are probably most effective at
preventing addiction
The biological definition of addiction states that addictive substances
activate the VTA pathway
The mesolimbic pathway is made up of neurons that produce
dopamine
The mesolimbic pathways begins in the VTA and terminates in the
nucleus accumbens, amygdala, and prefrontal cortex
The use of clonidine to treat alcohol/opiate addiction is an example of which pharmaceutical treatment strategy?
withdrawal maintainence
Administration of Methadone to heroin addicts is an example of
agonist substitution
The reason antagonist administration strategies are often unsuccessful is due to
patient non-compliance
What proportion of patients addicted to alcohol/drugs have also been diagnosed with a psychiatric disease?
1/3
The following are all advantages of the partial-agonist substitution pharmacological approach
- dec w/d sx
-does not induce abuse
-reduces cravings
Stress impacts addiction in all of the following ways
-stress and addiction share similar neurobiological pathways
-stress increases the likelihood of substance abuse
-stress increases the likelihood of craving and relapse
The “Rat Park” experiments, by Bruce Alexander, demonstrated that addiction rates are powerfully determined by
Social and environmental factors
The use of Chantix to help people stop using nicotine is an example of what kind of pharmaceutical approach?
Partial agonist substitution